R-loop resolution promotes co-transcriptional chromatin silencing

Nascent non-coding RNA can mediate chromatin silencing, however mechanistically this process is poorly understood. Here the authors show that resolution of an R-loop during 3'-end processing of a plant antisense transcript recruits chromatin modifiers to promote chromatin silencing.

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Autores principales:	Congyao Xu, Zhe Wu, Hong-Chao Duan, Xiaofeng Fang, Guifang Jia, Caroline Dean
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/64ef2beb98ae4a4d80c3b24ddfb29d13
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spelling	oai:doaj.org-article:64ef2beb98ae4a4d80c3b24ddfb29d132021-12-02T13:17:40ZR-loop resolution promotes co-transcriptional chromatin silencing10.1038/s41467-021-22083-62041-1723https://doaj.org/article/64ef2beb98ae4a4d80c3b24ddfb29d132021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22083-6https://doaj.org/toc/2041-1723Nascent non-coding RNA can mediate chromatin silencing, however mechanistically this process is poorly understood. Here the authors show that resolution of an R-loop during 3'-end processing of a plant antisense transcript recruits chromatin modifiers to promote chromatin silencing.Congyao XuZhe WuHong-Chao DuanXiaofeng FangGuifang JiaCaroline DeanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Congyao Xu Zhe Wu Hong-Chao Duan Xiaofeng Fang Guifang Jia Caroline Dean R-loop resolution promotes co-transcriptional chromatin silencing
description	Nascent non-coding RNA can mediate chromatin silencing, however mechanistically this process is poorly understood. Here the authors show that resolution of an R-loop during 3'-end processing of a plant antisense transcript recruits chromatin modifiers to promote chromatin silencing.
format	article
author	Congyao Xu Zhe Wu Hong-Chao Duan Xiaofeng Fang Guifang Jia Caroline Dean
author_facet	Congyao Xu Zhe Wu Hong-Chao Duan Xiaofeng Fang Guifang Jia Caroline Dean
author_sort	Congyao Xu
title	R-loop resolution promotes co-transcriptional chromatin silencing
title_short	R-loop resolution promotes co-transcriptional chromatin silencing
title_full	R-loop resolution promotes co-transcriptional chromatin silencing
title_fullStr	R-loop resolution promotes co-transcriptional chromatin silencing
title_full_unstemmed	R-loop resolution promotes co-transcriptional chromatin silencing
title_sort	r-loop resolution promotes co-transcriptional chromatin silencing
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/64ef2beb98ae4a4d80c3b24ddfb29d13
work_keys_str_mv	AT congyaoxu rloopresolutionpromotescotranscriptionalchromatinsilencing AT zhewu rloopresolutionpromotescotranscriptionalchromatinsilencing AT hongchaoduan rloopresolutionpromotescotranscriptionalchromatinsilencing AT xiaofengfang rloopresolutionpromotescotranscriptionalchromatinsilencing AT guifangjia rloopresolutionpromotescotranscriptionalchromatinsilencing AT carolinedean rloopresolutionpromotescotranscriptionalchromatinsilencing
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R-loop resolution promotes co-transcriptional chromatin silencing

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