Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus
<strong>Noni (<em>Morinda citrifolia</em>) Increase Immune Response in Mice (<em>Mus musculus</em>) Infected <em>Staphylococcus aureus</em>. </strong>Infection disease caused by bacteria is one of the illness in several developing countries including i...
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| Formato: | article |
| Lenguaje: | EN ID |
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Universitas Nahdlatul Ulama Surabaya
2015
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| Acceso en línea: | https://doaj.org/article/64efabbdf9814e21bfa2ede20a040ae9 |
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| Sumario: | <strong>Noni (<em>Morinda citrifolia</em>) Increase Immune Response in Mice (<em>Mus musculus</em>) Infected <em>Staphylococcus aureus</em>. </strong>Infection disease caused by bacteria is one of the illness in several developing countries including in Indonesia, with high mortality rate. Infection of <em>S. aureus</em> as the cause of problem resistance for antibiotic or multi drug resistance are giving the therapy of drug itself with change to medical herbal. The aim of this study is known the role of <em>M.citrifolia</em> extract to increase immune response of mice with infectioned of <em>S. aureus</em>. Mice were divided into two groups there are Non Infection and infection. Non Infection is without <em>S. aureus</em> and than infection has <em>S. aureus</em>. The each groups are including control, dose 1 (25 mg/kg BW), dose 2 (100 mg/kg BW), and dose 3 (300 mg/kg BW). Relative number of lymphocyte T cell (CD4+) subsets was measured using the BD FACSCaliburTM Flowcytometer. Data were analyzed using Analysis of Varians (p<0,05) and using SPSS 16 for windows. The result showed that administration of <em>M. citrifolia</em> crude extract in non infection groups was significantly increase the relative amounts T cell subsets (CD4+). Noni fruit extract can used as prevention therapy on infection disease of <em>S. aureus</em> bacteria because it contains active compounds that are anti-inflammation |
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