Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus

Noni (Morinda citrifolia) Increase Immune Response in Mice (Mus musculus) Infected Staphylococcus aureus. Infection disease caused by bacteria is one of the illness in several developing countries including i...

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Autor principal:	Mufidah Zumrotul
Formato:	article
Lenguaje:	EN ID
Publicado:	Universitas Nahdlatul Ulama Surabaya 2015
Materias:	Mengkudu Staphylococcus aureus limfosit T CD4+ Nursing RT1-120 Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/64efabbdf9814e21bfa2ede20a040ae9
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spelling	oai:doaj.org-article:64efabbdf9814e21bfa2ede20a040ae92021-12-02T05:59:51ZBuah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus1978-6743https://doaj.org/article/64efabbdf9814e21bfa2ede20a040ae92015-11-01T00:00:00Zhttp://journal.unusa.ac.id/index.php/jhs/article/view/35https://doaj.org/toc/1978-6743<strong>Noni (<em>Morinda citrifolia</em>) Increase Immune Response in Mice (<em>Mus musculus</em>) Infected <em>Staphylococcus aureus</em>. </strong>Infection disease caused by bacteria is one of the illness in several developing countries including in Indonesia, with high mortality rate. Infection of <em>S. aureus</em> as the cause of problem resistance for antibiotic or multi drug resistance are giving the therapy of drug itself with change to medical herbal. The aim of this study is known the role of <em>M.citrifolia</em> extract to increase immune response of mice with infectioned of <em>S. aureus</em>. Mice were divided into two groups there are Non Infection and infection. Non Infection is without <em>S. aureus</em> and than infection has <em>S. aureus</em>. The each groups are including control, dose 1 (25 mg/kg BW), dose 2 (100 mg/kg BW), and dose 3 (300 mg/kg BW). Relative number of lymphocyte T cell (CD4+) subsets was measured using the BD FACSCaliburTM Flowcytometer. Data were analyzed using Analysis of Varians (p<0,05) and using SPSS 16 for windows. The result showed that administration of <em>M. citrifolia</em> crude extract in non infection groups was significantly increase the relative amounts T cell subsets (CD4+). Noni fruit extract can used as prevention therapy on infection disease of <em>S. aureus</em> bacteria because it contains active compounds that are anti-inflammationMufidah ZumrotulUniversitas Nahdlatul Ulama SurabayaarticleMengkuduStaphylococcusaureuslimfositTCD4+NursingRT1-120Medicine (General)R5-920ENIDJurnal Ilmiah Kesehatan, Vol 6, Iss 2 (2015)
institution	DOAJ
collection	DOAJ
language	EN ID
topic	Mengkudu Staphylococcus aureus limfosit T CD4+ Nursing RT1-120 Medicine (General) R5-920
spellingShingle	Mengkudu Staphylococcus aureus limfosit T CD4+ Nursing RT1-120 Medicine (General) R5-920 Mufidah Zumrotul Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus
description	<strong>Noni (<em>Morinda citrifolia</em>) Increase Immune Response in Mice (<em>Mus musculus</em>) Infected <em>Staphylococcus aureus</em>. </strong>Infection disease caused by bacteria is one of the illness in several developing countries including in Indonesia, with high mortality rate. Infection of <em>S. aureus</em> as the cause of problem resistance for antibiotic or multi drug resistance are giving the therapy of drug itself with change to medical herbal. The aim of this study is known the role of <em>M.citrifolia</em> extract to increase immune response of mice with infectioned of <em>S. aureus</em>. Mice were divided into two groups there are Non Infection and infection. Non Infection is without <em>S. aureus</em> and than infection has <em>S. aureus</em>. The each groups are including control, dose 1 (25 mg/kg BW), dose 2 (100 mg/kg BW), and dose 3 (300 mg/kg BW). Relative number of lymphocyte T cell (CD4+) subsets was measured using the BD FACSCaliburTM Flowcytometer. Data were analyzed using Analysis of Varians (p<0,05) and using SPSS 16 for windows. The result showed that administration of <em>M. citrifolia</em> crude extract in non infection groups was significantly increase the relative amounts T cell subsets (CD4+). Noni fruit extract can used as prevention therapy on infection disease of <em>S. aureus</em> bacteria because it contains active compounds that are anti-inflammation
format	article
author	Mufidah Zumrotul
author_facet	Mufidah Zumrotul
author_sort	Mufidah Zumrotul
title	Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus
title_short	Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus
title_full	Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus
title_fullStr	Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus
title_full_unstemmed	Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus
title_sort	buah mengkudu (morinda citrifolia) meningkatkan respon imun mencit (mus musculus) terhadap infeksi bakteri staphylococcus aureus
publisher	Universitas Nahdlatul Ulama Surabaya
publishDate	2015
url	https://doaj.org/article/64efabbdf9814e21bfa2ede20a040ae9
work_keys_str_mv	AT mufidahzumrotul buahmengkudumorindacitrifoliameningkatkanresponimunmencitmusmusculusterhadapinfeksibakteristaphylococcusaureus
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Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus

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