Pitavastatin: focus on safety and drug interactions

Pitavastatin is a drug from the group of HMG-CoA reductase inhibitors, which has good lipid-lowering efficacy and has no significant effect on the risk of diabetes mellitus. This drug is non significantly metabolized by the P450 cytochrome system, which minimizes the risk of possible drug-drug inter...

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Autores principales:	Larisa O. Minushkina, Dmitry A. Zateyshchikov
Formato:	article
Lenguaje:	EN RU
Publicado:	Concilium Medicum 2021
Materias:	pitavastatin safety drug interactions cytochrome transporter Diseases of the circulatory (Cardiovascular) system RC666-701 Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/64f2f979611d4d8f8eeeb8ca730ad066
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id	oai:doaj.org-article:64f2f979611d4d8f8eeeb8ca730ad066
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spelling	oai:doaj.org-article:64f2f979611d4d8f8eeeb8ca730ad0662021-12-01T22:07:01ZPitavastatin: focus on safety and drug interactions2221-71852658-570710.26442/22217185.2021.1.200634https://doaj.org/article/64f2f979611d4d8f8eeeb8ca730ad0662021-05-01T00:00:00Zhttps://cardiosomatics.orscience.ru/2221-7185/article/viewFile/71039/51893https://doaj.org/toc/2221-7185https://doaj.org/toc/2658-5707Pitavastatin is a drug from the group of HMG-CoA reductase inhibitors, which has good lipid-lowering efficacy and has no significant effect on the risk of diabetes mellitus. This drug is non significantly metabolized by the P450 cytochrome system, which minimizes the risk of possible drug-drug interactions. Peptide organic anionic transporter inhibitors also may affect the efficacy and safety of the drug. This review summarizes the data on the problems of drug interactions of pitavastatin.Larisa O. MinushkinaDmitry A. ZateyshchikovConcilium Medicumarticlepitavastatinsafetydrug interactionscytochrometransporterDiseases of the circulatory (Cardiovascular) systemRC666-701Diseases of the endocrine glands. Clinical endocrinologyRC648-665ENRUКардиоСоматика, Vol 12, Iss 1, Pp 48-53 (2021)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	pitavastatin safety drug interactions cytochrome transporter Diseases of the circulatory (Cardiovascular) system RC666-701 Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	pitavastatin safety drug interactions cytochrome transporter Diseases of the circulatory (Cardiovascular) system RC666-701 Diseases of the endocrine glands. Clinical endocrinology RC648-665 Larisa O. Minushkina Dmitry A. Zateyshchikov Pitavastatin: focus on safety and drug interactions
description	Pitavastatin is a drug from the group of HMG-CoA reductase inhibitors, which has good lipid-lowering efficacy and has no significant effect on the risk of diabetes mellitus. This drug is non significantly metabolized by the P450 cytochrome system, which minimizes the risk of possible drug-drug interactions. Peptide organic anionic transporter inhibitors also may affect the efficacy and safety of the drug. This review summarizes the data on the problems of drug interactions of pitavastatin.
format	article
author	Larisa O. Minushkina Dmitry A. Zateyshchikov
author_facet	Larisa O. Minushkina Dmitry A. Zateyshchikov
author_sort	Larisa O. Minushkina
title	Pitavastatin: focus on safety and drug interactions
title_short	Pitavastatin: focus on safety and drug interactions
title_full	Pitavastatin: focus on safety and drug interactions
title_fullStr	Pitavastatin: focus on safety and drug interactions
title_full_unstemmed	Pitavastatin: focus on safety and drug interactions
title_sort	pitavastatin: focus on safety and drug interactions
publisher	Concilium Medicum
publishDate	2021
url	https://doaj.org/article/64f2f979611d4d8f8eeeb8ca730ad066
work_keys_str_mv	AT larisaominushkina pitavastatinfocusonsafetyanddruginteractions AT dmitryazateyshchikov pitavastatinfocusonsafetyanddruginteractions
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Pitavastatin: focus on safety and drug interactions

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