Pyruvate Homeostasis as a Determinant of Parasite Growth and Metabolic Plasticity in <named-content content-type="genus-species">Toxoplasma gondii</named-content>

Pyruvate Homeostasis as a Determinant of Parasite Growth and Metabolic Plasticity in <named-content content-type="genus-species">Toxoplasma gondii</named-content>

ABSTRACT Toxoplasma gondii is a widespread intracellular pathogen infecting humans and a variety of animals. Previous studies have shown that Toxoplasma uses glucose and glutamine as the main carbon sources to support asexual reproduction, but neither nutrient is essential. Such metabolic flexibilit...

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Bibliographic Details
Main Authors: Ningbo Xia, Shu Ye, Xiaohan Liang, Pu Chen, Yanqin Zhou, Rui Fang, Junlong Zhao, Nishith Gupta, Shuzhen Yang, Jing Yuan, Bang Shen
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
Toxoplasma
apicoplast
lactate
metabolic flexibility
pyruvate kinase
Microbiology
QR1-502
Online Access:https://doaj.org/article/64f32c2546cf4338a4b51309136ea13c
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