Antibody-controlled actuation of DNA-based molecular circuits

Existing DNA based circuits, designed to perform logic operations and signal processing, are generally responsive to DNA or RNA inputs. Here, the authors show that antibodies can actuate DNA logic gates, opening the way to applications of DNA computing in diagnostics and biomedicine.

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Detalles Bibliográficos
Autores principales: Wouter Engelen, Lenny H. H. Meijer, Bram Somers, Tom F. A. de Greef, Maarten Merkx
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/64f594ec6a344af8979cb00882632e2f
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Descripción
Sumario:Existing DNA based circuits, designed to perform logic operations and signal processing, are generally responsive to DNA or RNA inputs. Here, the authors show that antibodies can actuate DNA logic gates, opening the way to applications of DNA computing in diagnostics and biomedicine.