Antibody-controlled actuation of DNA-based molecular circuits

Existing DNA based circuits, designed to perform logic operations and signal processing, are generally responsive to DNA or RNA inputs. Here, the authors show that antibodies can actuate DNA logic gates, opening the way to applications of DNA computing in diagnostics and biomedicine.

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Autores principales: Wouter Engelen, Lenny H. H. Meijer, Bram Somers, Tom F. A. de Greef, Maarten Merkx
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/64f594ec6a344af8979cb00882632e2f
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spelling oai:doaj.org-article:64f594ec6a344af8979cb00882632e2f2021-12-02T14:42:06ZAntibody-controlled actuation of DNA-based molecular circuits10.1038/ncomms144732041-1723https://doaj.org/article/64f594ec6a344af8979cb00882632e2f2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14473https://doaj.org/toc/2041-1723Existing DNA based circuits, designed to perform logic operations and signal processing, are generally responsive to DNA or RNA inputs. Here, the authors show that antibodies can actuate DNA logic gates, opening the way to applications of DNA computing in diagnostics and biomedicine.Wouter EngelenLenny H. H. MeijerBram SomersTom F. A. de GreefMaarten MerkxNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wouter Engelen
Lenny H. H. Meijer
Bram Somers
Tom F. A. de Greef
Maarten Merkx
Antibody-controlled actuation of DNA-based molecular circuits
description Existing DNA based circuits, designed to perform logic operations and signal processing, are generally responsive to DNA or RNA inputs. Here, the authors show that antibodies can actuate DNA logic gates, opening the way to applications of DNA computing in diagnostics and biomedicine.
format article
author Wouter Engelen
Lenny H. H. Meijer
Bram Somers
Tom F. A. de Greef
Maarten Merkx
author_facet Wouter Engelen
Lenny H. H. Meijer
Bram Somers
Tom F. A. de Greef
Maarten Merkx
author_sort Wouter Engelen
title Antibody-controlled actuation of DNA-based molecular circuits
title_short Antibody-controlled actuation of DNA-based molecular circuits
title_full Antibody-controlled actuation of DNA-based molecular circuits
title_fullStr Antibody-controlled actuation of DNA-based molecular circuits
title_full_unstemmed Antibody-controlled actuation of DNA-based molecular circuits
title_sort antibody-controlled actuation of dna-based molecular circuits
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/64f594ec6a344af8979cb00882632e2f
work_keys_str_mv AT wouterengelen antibodycontrolledactuationofdnabasedmolecularcircuits
AT lennyhhmeijer antibodycontrolledactuationofdnabasedmolecularcircuits
AT bramsomers antibodycontrolledactuationofdnabasedmolecularcircuits
AT tomfadegreef antibodycontrolledactuationofdnabasedmolecularcircuits
AT maartenmerkx antibodycontrolledactuationofdnabasedmolecularcircuits
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