Antibody-controlled actuation of DNA-based molecular circuits
Existing DNA based circuits, designed to perform logic operations and signal processing, are generally responsive to DNA or RNA inputs. Here, the authors show that antibodies can actuate DNA logic gates, opening the way to applications of DNA computing in diagnostics and biomedicine.
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Nature Portfolio
2017
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oai:doaj.org-article:64f594ec6a344af8979cb00882632e2f2021-12-02T14:42:06ZAntibody-controlled actuation of DNA-based molecular circuits10.1038/ncomms144732041-1723https://doaj.org/article/64f594ec6a344af8979cb00882632e2f2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14473https://doaj.org/toc/2041-1723Existing DNA based circuits, designed to perform logic operations and signal processing, are generally responsive to DNA or RNA inputs. Here, the authors show that antibodies can actuate DNA logic gates, opening the way to applications of DNA computing in diagnostics and biomedicine.Wouter EngelenLenny H. H. MeijerBram SomersTom F. A. de GreefMaarten MerkxNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017) |
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Science Q Wouter Engelen Lenny H. H. Meijer Bram Somers Tom F. A. de Greef Maarten Merkx Antibody-controlled actuation of DNA-based molecular circuits |
description |
Existing DNA based circuits, designed to perform logic operations and signal processing, are generally responsive to DNA or RNA inputs. Here, the authors show that antibodies can actuate DNA logic gates, opening the way to applications of DNA computing in diagnostics and biomedicine. |
format |
article |
author |
Wouter Engelen Lenny H. H. Meijer Bram Somers Tom F. A. de Greef Maarten Merkx |
author_facet |
Wouter Engelen Lenny H. H. Meijer Bram Somers Tom F. A. de Greef Maarten Merkx |
author_sort |
Wouter Engelen |
title |
Antibody-controlled actuation of DNA-based molecular circuits |
title_short |
Antibody-controlled actuation of DNA-based molecular circuits |
title_full |
Antibody-controlled actuation of DNA-based molecular circuits |
title_fullStr |
Antibody-controlled actuation of DNA-based molecular circuits |
title_full_unstemmed |
Antibody-controlled actuation of DNA-based molecular circuits |
title_sort |
antibody-controlled actuation of dna-based molecular circuits |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/64f594ec6a344af8979cb00882632e2f |
work_keys_str_mv |
AT wouterengelen antibodycontrolledactuationofdnabasedmolecularcircuits AT lennyhhmeijer antibodycontrolledactuationofdnabasedmolecularcircuits AT bramsomers antibodycontrolledactuationofdnabasedmolecularcircuits AT tomfadegreef antibodycontrolledactuationofdnabasedmolecularcircuits AT maartenmerkx antibodycontrolledactuationofdnabasedmolecularcircuits |
_version_ |
1718389811620872192 |