Functional characterization of domains of IPS-1 using an inducible oligomerization system.
The innate immune system recognizes viral nucleic acids and stimulates cellular antiviral responses. Intracellular detection of viral RNA is mediated by the Retinoic acid inducible gene (RIG)-I Like Receptor (RLR), leading to production of type I interferon (IFN) and pro-inflammatory cytokines. Once...
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Auteurs principaux: | , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2013
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Accès en ligne: | https://doaj.org/article/64fceae48bba4d2698d93f9505f2a71b |
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