Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa

Glycogen storage disease type IXa (GSD IXa) is a rare genetic disorder characterized by phosphorylase kinase (PhK) deficiency, which leads to excessive glycogen accumulation in the liver. Urinary cells (UCs) were isolated from a GSD IXa patient and reprogrammed into induced pluripotent stem cells (i...

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Autores principales:	Yongbo Shin, Seon Ju Mun, Jaeseo Lee, Kyung-Sook Chung, Misuk Kim, Chong Kun Cheon, Myung Jin Son
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Liver Organoids GSD IXa iPSCs Urinary cells Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/65004ed9fae84708a42b793961f434a6
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spelling	oai:doaj.org-article:65004ed9fae84708a42b793961f434a62021-11-04T04:27:41ZGeneration of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa1873-506110.1016/j.scr.2021.102584https://doaj.org/article/65004ed9fae84708a42b793961f434a62021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1873506121004311https://doaj.org/toc/1873-5061Glycogen storage disease type IXa (GSD IXa) is a rare genetic disorder characterized by phosphorylase kinase (PhK) deficiency, which leads to excessive glycogen accumulation in the liver. Urinary cells (UCs) were isolated from a GSD IXa patient and reprogrammed into induced pluripotent stem cells (iPSCs) using Sendai virus. The established iPSC line, KRIBBi003-A, exhibited pluripotency marker expression and a normal karyotype. The differentiation capacity of the cell line was confirmed by the differentiation of the three germ layers in vitro. The established iPSC line is a potential useful resource for disease modeling of GSD IXa.Yongbo ShinSeon Ju MunJaeseo LeeKyung-Sook ChungMisuk KimChong Kun CheonMyung Jin SonElsevierarticleLiverOrganoidsGSD IXaiPSCsUrinary cellsBiology (General)QH301-705.5ENStem Cell Research, Vol 57, Iss , Pp 102584- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Liver Organoids GSD IXa iPSCs Urinary cells Biology (General) QH301-705.5
spellingShingle	Liver Organoids GSD IXa iPSCs Urinary cells Biology (General) QH301-705.5 Yongbo Shin Seon Ju Mun Jaeseo Lee Kyung-Sook Chung Misuk Kim Chong Kun Cheon Myung Jin Son Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa
description	Glycogen storage disease type IXa (GSD IXa) is a rare genetic disorder characterized by phosphorylase kinase (PhK) deficiency, which leads to excessive glycogen accumulation in the liver. Urinary cells (UCs) were isolated from a GSD IXa patient and reprogrammed into induced pluripotent stem cells (iPSCs) using Sendai virus. The established iPSC line, KRIBBi003-A, exhibited pluripotency marker expression and a normal karyotype. The differentiation capacity of the cell line was confirmed by the differentiation of the three germ layers in vitro. The established iPSC line is a potential useful resource for disease modeling of GSD IXa.
format	article
author	Yongbo Shin Seon Ju Mun Jaeseo Lee Kyung-Sook Chung Misuk Kim Chong Kun Cheon Myung Jin Son
author_facet	Yongbo Shin Seon Ju Mun Jaeseo Lee Kyung-Sook Chung Misuk Kim Chong Kun Cheon Myung Jin Son
author_sort	Yongbo Shin
title	Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa
title_short	Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa
title_full	Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa
title_fullStr	Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa
title_full_unstemmed	Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa
title_sort	generation of human induced pluripotent stem cell line, kribbi003-a, from urinary cells of a patient with glycogen storage disease type ixa
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/65004ed9fae84708a42b793961f434a6
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Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa

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