An evolutionary hotspot defines functional differences between CRYPTOCHROMES
The molecular mechanisms that define the periodicity or rate of the circadian clock are not well understood. Here the authors use a multidisciplinary approach and identify a mechanism for period regulation that depends on the affinity of the core clock proteins for one another.
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Nature Portfolio
2018
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oai:doaj.org-article:65074cf0d73e41918a1780ff7d99d7662021-12-02T15:34:27ZAn evolutionary hotspot defines functional differences between CRYPTOCHROMES10.1038/s41467-018-03503-62041-1723https://doaj.org/article/65074cf0d73e41918a1780ff7d99d7662018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03503-6https://doaj.org/toc/2041-1723The molecular mechanisms that define the periodicity or rate of the circadian clock are not well understood. Here the authors use a multidisciplinary approach and identify a mechanism for period regulation that depends on the affinity of the core clock proteins for one another.Clark RosensweigKimberly A. ReynoldsPeng GaoIsara LaothamatasYongli ShanRama RanganathanJoseph S. TakahashiCarla B. GreenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018) |
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Science Q Clark Rosensweig Kimberly A. Reynolds Peng Gao Isara Laothamatas Yongli Shan Rama Ranganathan Joseph S. Takahashi Carla B. Green An evolutionary hotspot defines functional differences between CRYPTOCHROMES |
description |
The molecular mechanisms that define the periodicity or rate of the circadian clock are not well understood. Here the authors use a multidisciplinary approach and identify a mechanism for period regulation that depends on the affinity of the core clock proteins for one another. |
format |
article |
author |
Clark Rosensweig Kimberly A. Reynolds Peng Gao Isara Laothamatas Yongli Shan Rama Ranganathan Joseph S. Takahashi Carla B. Green |
author_facet |
Clark Rosensweig Kimberly A. Reynolds Peng Gao Isara Laothamatas Yongli Shan Rama Ranganathan Joseph S. Takahashi Carla B. Green |
author_sort |
Clark Rosensweig |
title |
An evolutionary hotspot defines functional differences between CRYPTOCHROMES |
title_short |
An evolutionary hotspot defines functional differences between CRYPTOCHROMES |
title_full |
An evolutionary hotspot defines functional differences between CRYPTOCHROMES |
title_fullStr |
An evolutionary hotspot defines functional differences between CRYPTOCHROMES |
title_full_unstemmed |
An evolutionary hotspot defines functional differences between CRYPTOCHROMES |
title_sort |
evolutionary hotspot defines functional differences between cryptochromes |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/65074cf0d73e41918a1780ff7d99d766 |
work_keys_str_mv |
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