An evolutionary hotspot defines functional differences between CRYPTOCHROMES

The molecular mechanisms that define the periodicity or rate of the circadian clock are not well understood. Here the authors use a multidisciplinary approach and identify a mechanism for period regulation that depends on the affinity of the core clock proteins for one another.

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Autores principales: Clark Rosensweig, Kimberly A. Reynolds, Peng Gao, Isara Laothamatas, Yongli Shan, Rama Ranganathan, Joseph S. Takahashi, Carla B. Green
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/65074cf0d73e41918a1780ff7d99d766
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spelling oai:doaj.org-article:65074cf0d73e41918a1780ff7d99d7662021-12-02T15:34:27ZAn evolutionary hotspot defines functional differences between CRYPTOCHROMES10.1038/s41467-018-03503-62041-1723https://doaj.org/article/65074cf0d73e41918a1780ff7d99d7662018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03503-6https://doaj.org/toc/2041-1723The molecular mechanisms that define the periodicity or rate of the circadian clock are not well understood. Here the authors use a multidisciplinary approach and identify a mechanism for period regulation that depends on the affinity of the core clock proteins for one another.Clark RosensweigKimberly A. ReynoldsPeng GaoIsara LaothamatasYongli ShanRama RanganathanJoseph S. TakahashiCarla B. GreenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Clark Rosensweig
Kimberly A. Reynolds
Peng Gao
Isara Laothamatas
Yongli Shan
Rama Ranganathan
Joseph S. Takahashi
Carla B. Green
An evolutionary hotspot defines functional differences between CRYPTOCHROMES
description The molecular mechanisms that define the periodicity or rate of the circadian clock are not well understood. Here the authors use a multidisciplinary approach and identify a mechanism for period regulation that depends on the affinity of the core clock proteins for one another.
format article
author Clark Rosensweig
Kimberly A. Reynolds
Peng Gao
Isara Laothamatas
Yongli Shan
Rama Ranganathan
Joseph S. Takahashi
Carla B. Green
author_facet Clark Rosensweig
Kimberly A. Reynolds
Peng Gao
Isara Laothamatas
Yongli Shan
Rama Ranganathan
Joseph S. Takahashi
Carla B. Green
author_sort Clark Rosensweig
title An evolutionary hotspot defines functional differences between CRYPTOCHROMES
title_short An evolutionary hotspot defines functional differences between CRYPTOCHROMES
title_full An evolutionary hotspot defines functional differences between CRYPTOCHROMES
title_fullStr An evolutionary hotspot defines functional differences between CRYPTOCHROMES
title_full_unstemmed An evolutionary hotspot defines functional differences between CRYPTOCHROMES
title_sort evolutionary hotspot defines functional differences between cryptochromes
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/65074cf0d73e41918a1780ff7d99d766
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