Impact of PET/CT among patients with suspected mycotic aortic aneurysms.

<h4>Purpose</h4>To determine the impact of 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) on clinical management in patients with suspected mycotic aortic aneurysms (MAA).<h4>Materials and methods</h4>For this observational cohort study...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Lars Husmann, Martin W Huellner, Hannes Gruenig, Nadia Eberhard, Carlos A Mestres, Zoran Rancic, Barbara Hasse
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6513423b41af481d9a7833d5bd5a4795
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6513423b41af481d9a7833d5bd5a4795
record_format	dspace
spelling	oai:doaj.org-article:6513423b41af481d9a7833d5bd5a47952021-12-02T20:16:47ZImpact of PET/CT among patients with suspected mycotic aortic aneurysms.1932-620310.1371/journal.pone.0258702https://doaj.org/article/6513423b41af481d9a7833d5bd5a47952021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0258702https://doaj.org/toc/1932-6203<h4>Purpose</h4>To determine the impact of 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) on clinical management in patients with suspected mycotic aortic aneurysms (MAA).<h4>Materials and methods</h4>For this observational cohort study 101 PET/CT were acquired in 50 patients, thereof 50 for the initial diagnosis/baseline scan, 51 for follow-up. Impact on patient management was defined in three categories: PET/CT results were "confirmed" (by clinical follow-up), "suspected" (conclusive, not confirmed), or "misleading" (proven wrong by follow-up). For clinical follow-up patient data were recorded at the time of imaging, and at the latest recorded clinical visit. It included patient demographics, clinical information, laboratory data, results of microbiology and other diagnostic procedures, information about treatment, and patient's general health condition.<h4>Results</h4>In four patients (8%) no clinical follow-up was feasible, the other 46 patients were clinically followed for a median of 898 days (IQR 320-4105). The combined evaluation of all 101 PET/CT demonstrated an impact on patient management in 78,5% of cases (48,5% confirmed, 30% suspected). Results of 21,5% of the PET/CT examinations were misleading. Respective values at baseline and at follow-up were: impact on patient management in 82% and 74,5% (70% and 27.5% confirmed, and 12% and 47% suspected), misleading cases in 18% and 25.5%.<h4>Conclusion</h4>In MAA, PET/CT has a high impact on patient management, which is more pronounced with baseline than with follow-up examinations. However, PET/CT results may be misleading in a smaller proportion of cases.Lars HusmannMartin W HuellnerHannes GruenigNadia EberhardCarlos A MestresZoran RancicBarbara HassePublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 10, p e0258702 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Lars Husmann Martin W Huellner Hannes Gruenig Nadia Eberhard Carlos A Mestres Zoran Rancic Barbara Hasse Impact of PET/CT among patients with suspected mycotic aortic aneurysms.
description	<h4>Purpose</h4>To determine the impact of 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) on clinical management in patients with suspected mycotic aortic aneurysms (MAA).<h4>Materials and methods</h4>For this observational cohort study 101 PET/CT were acquired in 50 patients, thereof 50 for the initial diagnosis/baseline scan, 51 for follow-up. Impact on patient management was defined in three categories: PET/CT results were "confirmed" (by clinical follow-up), "suspected" (conclusive, not confirmed), or "misleading" (proven wrong by follow-up). For clinical follow-up patient data were recorded at the time of imaging, and at the latest recorded clinical visit. It included patient demographics, clinical information, laboratory data, results of microbiology and other diagnostic procedures, information about treatment, and patient's general health condition.<h4>Results</h4>In four patients (8%) no clinical follow-up was feasible, the other 46 patients were clinically followed for a median of 898 days (IQR 320-4105). The combined evaluation of all 101 PET/CT demonstrated an impact on patient management in 78,5% of cases (48,5% confirmed, 30% suspected). Results of 21,5% of the PET/CT examinations were misleading. Respective values at baseline and at follow-up were: impact on patient management in 82% and 74,5% (70% and 27.5% confirmed, and 12% and 47% suspected), misleading cases in 18% and 25.5%.<h4>Conclusion</h4>In MAA, PET/CT has a high impact on patient management, which is more pronounced with baseline than with follow-up examinations. However, PET/CT results may be misleading in a smaller proportion of cases.
format	article
author	Lars Husmann Martin W Huellner Hannes Gruenig Nadia Eberhard Carlos A Mestres Zoran Rancic Barbara Hasse
author_facet	Lars Husmann Martin W Huellner Hannes Gruenig Nadia Eberhard Carlos A Mestres Zoran Rancic Barbara Hasse
author_sort	Lars Husmann
title	Impact of PET/CT among patients with suspected mycotic aortic aneurysms.
title_short	Impact of PET/CT among patients with suspected mycotic aortic aneurysms.
title_full	Impact of PET/CT among patients with suspected mycotic aortic aneurysms.
title_fullStr	Impact of PET/CT among patients with suspected mycotic aortic aneurysms.
title_full_unstemmed	Impact of PET/CT among patients with suspected mycotic aortic aneurysms.
title_sort	impact of pet/ct among patients with suspected mycotic aortic aneurysms.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/6513423b41af481d9a7833d5bd5a4795
work_keys_str_mv	AT larshusmann impactofpetctamongpatientswithsuspectedmycoticaorticaneurysms AT martinwhuellner impactofpetctamongpatientswithsuspectedmycoticaorticaneurysms AT hannesgruenig impactofpetctamongpatientswithsuspectedmycoticaorticaneurysms AT nadiaeberhard impactofpetctamongpatientswithsuspectedmycoticaorticaneurysms AT carlosamestres impactofpetctamongpatientswithsuspectedmycoticaorticaneurysms AT zoranrancic impactofpetctamongpatientswithsuspectedmycoticaorticaneurysms AT barbarahasse impactofpetctamongpatientswithsuspectedmycoticaorticaneurysms
_version_	1718374471383908352

Impact of PET/CT among patients with suspected mycotic aortic aneurysms.

Ejemplares similares