Barriers for efficacious hypoglycemic therapy in clinical practice (results of the Dialogue study)

Aim. To analyse factors hampering the achievement of compensation of carbohydrate metabolism in patients with type 2 diabetes mellitus treated for3 months with diabeton MB at a daily dose of 90-120 mg under real practical conditions. Materials and methods. This open study included 70 patients with...

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Autores principales:	Irina Evgen'evna Sapozhnikova, Elena Nikolaevna Anufrieva, Ekaterina Iosifovna Tarlovskaya, Alexander Anatol'evich Sobolev
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2010
Materias:	type 2 diabetes mellitus hypoglycemic therapy gliclazide mb hba1c level Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/6518a7cf4b174f3bac0972ff6d4a4961
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spelling	oai:doaj.org-article:6518a7cf4b174f3bac0972ff6d4a49612021-11-14T09:00:15ZBarriers for efficacious hypoglycemic therapy in clinical practice (results of the Dialogue study)2072-03512072-037810.14341/2072-0351-6058https://doaj.org/article/6518a7cf4b174f3bac0972ff6d4a49612010-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6058https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To analyse factors hampering the achievement of compensation of carbohydrate metabolism in patients with type 2 diabetes mellitus treated for3 months with diabeton MB at a daily dose of 90-120 mg under real practical conditions. Materials and methods. This open study included 70 patients with type 2 diabetes mellitus given gliclazide MB-based hypoglycemic therapy(90-120 mg/day); their HbA1c level was measured before and 3 months after the onset of therapy. Results. The treatment resulted in a significant decrease of the HbA1c level especially pronounced in patients capable of following the rational therapeuticstrategy. At the closing visit, each patient was prescribed a pathogenetically sound regime of combined hypoglycemic therapy. Conclusion. Poor efficacy of hypoglycemic treatment in real clinical practice is attributable to frequent prescription of monotherapy, untimely onsetof insulin administration, its correction and intensification to meet changing requirementsIrina Evgen'evna SapozhnikovaElena Nikolaevna AnufrievaEkaterina Iosifovna TarlovskayaAlexander Anatol'evich SobolevEndocrinology Research Centrearticletype 2 diabetes mellitushypoglycemic therapygliclazide mbhba1c levelNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 13, Iss 4, Pp 54-56 (2010)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	type 2 diabetes mellitus hypoglycemic therapy gliclazide mb hba1c level Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	type 2 diabetes mellitus hypoglycemic therapy gliclazide mb hba1c level Nutritional diseases. Deficiency diseases RC620-627 Irina Evgen'evna Sapozhnikova Elena Nikolaevna Anufrieva Ekaterina Iosifovna Tarlovskaya Alexander Anatol'evich Sobolev Barriers for efficacious hypoglycemic therapy in clinical practice (results of the Dialogue study)
description	Aim. To analyse factors hampering the achievement of compensation of carbohydrate metabolism in patients with type 2 diabetes mellitus treated for3 months with diabeton MB at a daily dose of 90-120 mg under real practical conditions. Materials and methods. This open study included 70 patients with type 2 diabetes mellitus given gliclazide MB-based hypoglycemic therapy(90-120 mg/day); their HbA1c level was measured before and 3 months after the onset of therapy. Results. The treatment resulted in a significant decrease of the HbA1c level especially pronounced in patients capable of following the rational therapeuticstrategy. At the closing visit, each patient was prescribed a pathogenetically sound regime of combined hypoglycemic therapy. Conclusion. Poor efficacy of hypoglycemic treatment in real clinical practice is attributable to frequent prescription of monotherapy, untimely onsetof insulin administration, its correction and intensification to meet changing requirements
format	article
author	Irina Evgen'evna Sapozhnikova Elena Nikolaevna Anufrieva Ekaterina Iosifovna Tarlovskaya Alexander Anatol'evich Sobolev
author_facet	Irina Evgen'evna Sapozhnikova Elena Nikolaevna Anufrieva Ekaterina Iosifovna Tarlovskaya Alexander Anatol'evich Sobolev
author_sort	Irina Evgen'evna Sapozhnikova
title	Barriers for efficacious hypoglycemic therapy in clinical practice (results of the Dialogue study)
title_short	Barriers for efficacious hypoglycemic therapy in clinical practice (results of the Dialogue study)
title_full	Barriers for efficacious hypoglycemic therapy in clinical practice (results of the Dialogue study)
title_fullStr	Barriers for efficacious hypoglycemic therapy in clinical practice (results of the Dialogue study)
title_full_unstemmed	Barriers for efficacious hypoglycemic therapy in clinical practice (results of the Dialogue study)
title_sort	barriers for efficacious hypoglycemic therapy in clinical practice (results of the dialogue study)
publisher	Endocrinology Research Centre
publishDate	2010
url	https://doaj.org/article/6518a7cf4b174f3bac0972ff6d4a4961
work_keys_str_mv	AT irinaevgenevnasapozhnikova barriersforefficacioushypoglycemictherapyinclinicalpracticeresultsofthedialoguestudy AT elenanikolaevnaanufrieva barriersforefficacioushypoglycemictherapyinclinicalpracticeresultsofthedialoguestudy AT ekaterinaiosifovnatarlovskaya barriersforefficacioushypoglycemictherapyinclinicalpracticeresultsofthedialoguestudy AT alexanderanatolevichsobolev barriersforefficacioushypoglycemictherapyinclinicalpracticeresultsofthedialoguestudy
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Barriers for efficacious hypoglycemic therapy in clinical practice (results of the Dialogue study)

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