In situ ultrastructures of two evolutionarily distant apicomplexan rhoptry secretion systems

The rhoptry is an apical secretory organelle of apicomplexan parasites that is essential for host cell invasion. Here, Mageswaran et al. provide in situ ultrastructures of rhoptries from two pathogens, revealing a conserved architecture including luminal filaments and a distinct docking mechanism.

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Detalles Bibliográficos
Autores principales: Shrawan Kumar Mageswaran, Amandine Guérin, Liam M. Theveny, William David Chen, Matthew Martinez, Maryse Lebrun, Boris Striepen, Yi-Wei Chang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/65277b58fe3c478dae8f5b0f288611d4
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Sumario:The rhoptry is an apical secretory organelle of apicomplexan parasites that is essential for host cell invasion. Here, Mageswaran et al. provide in situ ultrastructures of rhoptries from two pathogens, revealing a conserved architecture including luminal filaments and a distinct docking mechanism.