In situ ultrastructures of two evolutionarily distant apicomplexan rhoptry secretion systems
The rhoptry is an apical secretory organelle of apicomplexan parasites that is essential for host cell invasion. Here, Mageswaran et al. provide in situ ultrastructures of rhoptries from two pathogens, revealing a conserved architecture including luminal filaments and a distinct docking mechanism.
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Nature Portfolio
2021
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oai:doaj.org-article:65277b58fe3c478dae8f5b0f288611d42021-12-02T15:10:35ZIn situ ultrastructures of two evolutionarily distant apicomplexan rhoptry secretion systems10.1038/s41467-021-25309-92041-1723https://doaj.org/article/65277b58fe3c478dae8f5b0f288611d42021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25309-9https://doaj.org/toc/2041-1723The rhoptry is an apical secretory organelle of apicomplexan parasites that is essential for host cell invasion. Here, Mageswaran et al. provide in situ ultrastructures of rhoptries from two pathogens, revealing a conserved architecture including luminal filaments and a distinct docking mechanism.Shrawan Kumar MageswaranAmandine GuérinLiam M. ThevenyWilliam David ChenMatthew MartinezMaryse LebrunBoris StriepenYi-Wei ChangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
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Science Q Shrawan Kumar Mageswaran Amandine Guérin Liam M. Theveny William David Chen Matthew Martinez Maryse Lebrun Boris Striepen Yi-Wei Chang In situ ultrastructures of two evolutionarily distant apicomplexan rhoptry secretion systems |
description |
The rhoptry is an apical secretory organelle of apicomplexan parasites that is essential for host cell invasion. Here, Mageswaran et al. provide in situ ultrastructures of rhoptries from two pathogens, revealing a conserved architecture including luminal filaments and a distinct docking mechanism. |
format |
article |
author |
Shrawan Kumar Mageswaran Amandine Guérin Liam M. Theveny William David Chen Matthew Martinez Maryse Lebrun Boris Striepen Yi-Wei Chang |
author_facet |
Shrawan Kumar Mageswaran Amandine Guérin Liam M. Theveny William David Chen Matthew Martinez Maryse Lebrun Boris Striepen Yi-Wei Chang |
author_sort |
Shrawan Kumar Mageswaran |
title |
In situ ultrastructures of two evolutionarily distant apicomplexan rhoptry secretion systems |
title_short |
In situ ultrastructures of two evolutionarily distant apicomplexan rhoptry secretion systems |
title_full |
In situ ultrastructures of two evolutionarily distant apicomplexan rhoptry secretion systems |
title_fullStr |
In situ ultrastructures of two evolutionarily distant apicomplexan rhoptry secretion systems |
title_full_unstemmed |
In situ ultrastructures of two evolutionarily distant apicomplexan rhoptry secretion systems |
title_sort |
in situ ultrastructures of two evolutionarily distant apicomplexan rhoptry secretion systems |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/65277b58fe3c478dae8f5b0f288611d4 |
work_keys_str_mv |
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_version_ |
1718387692430950400 |