Intracellular construction of topology-controlled polypeptide nanostructures with diverse biological functions

The intracellular topology of a nanostructure plays a major role in its interactions with the cell and accordingly, its biological applications. Here, the authors design peptides that intracellularly polymerize into elastin-like polypeptides and assemble into various topologies, each of which exhibi...

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Autores principales:	Li-Li Li, Sheng-Lin Qiao, Wei-Jiao Liu, Yang Ma, Dong Wan, Jie Pan, Hao Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/65454839442b431f9918a47b2dec0800
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spelling	oai:doaj.org-article:65454839442b431f9918a47b2dec08002021-12-02T14:41:09ZIntracellular construction of topology-controlled polypeptide nanostructures with diverse biological functions10.1038/s41467-017-01296-82041-1723https://doaj.org/article/65454839442b431f9918a47b2dec08002017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01296-8https://doaj.org/toc/2041-1723The intracellular topology of a nanostructure plays a major role in its interactions with the cell and accordingly, its biological applications. Here, the authors design peptides that intracellularly polymerize into elastin-like polypeptides and assemble into various topologies, each of which exhibits a distinct set of biological functions.Li-Li LiSheng-Lin QiaoWei-Jiao LiuYang MaDong WanJie PanHao WangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Li-Li Li Sheng-Lin Qiao Wei-Jiao Liu Yang Ma Dong Wan Jie Pan Hao Wang Intracellular construction of topology-controlled polypeptide nanostructures with diverse biological functions
description	The intracellular topology of a nanostructure plays a major role in its interactions with the cell and accordingly, its biological applications. Here, the authors design peptides that intracellularly polymerize into elastin-like polypeptides and assemble into various topologies, each of which exhibits a distinct set of biological functions.
format	article
author	Li-Li Li Sheng-Lin Qiao Wei-Jiao Liu Yang Ma Dong Wan Jie Pan Hao Wang
author_facet	Li-Li Li Sheng-Lin Qiao Wei-Jiao Liu Yang Ma Dong Wan Jie Pan Hao Wang
author_sort	Li-Li Li
title	Intracellular construction of topology-controlled polypeptide nanostructures with diverse biological functions
title_short	Intracellular construction of topology-controlled polypeptide nanostructures with diverse biological functions
title_full	Intracellular construction of topology-controlled polypeptide nanostructures with diverse biological functions
title_fullStr	Intracellular construction of topology-controlled polypeptide nanostructures with diverse biological functions
title_full_unstemmed	Intracellular construction of topology-controlled polypeptide nanostructures with diverse biological functions
title_sort	intracellular construction of topology-controlled polypeptide nanostructures with diverse biological functions
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/65454839442b431f9918a47b2dec0800
work_keys_str_mv	AT lilili intracellularconstructionoftopologycontrolledpolypeptidenanostructureswithdiversebiologicalfunctions AT shenglinqiao intracellularconstructionoftopologycontrolledpolypeptidenanostructureswithdiversebiologicalfunctions AT weijiaoliu intracellularconstructionoftopologycontrolledpolypeptidenanostructureswithdiversebiologicalfunctions AT yangma intracellularconstructionoftopologycontrolledpolypeptidenanostructureswithdiversebiologicalfunctions AT dongwan intracellularconstructionoftopologycontrolledpolypeptidenanostructureswithdiversebiologicalfunctions AT jiepan intracellularconstructionoftopologycontrolledpolypeptidenanostructureswithdiversebiologicalfunctions AT haowang intracellularconstructionoftopologycontrolledpolypeptidenanostructureswithdiversebiologicalfunctions
_version_	1718389992792784896

Intracellular construction of topology-controlled polypeptide nanostructures with diverse biological functions

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