Optimising classification of Parkinson’s disease based on motor, olfactory, neuropsychiatric and sleep features

Abstract Olfactory loss, motor impairment, anxiety/depression, and REM-sleep behaviour disorder (RBD) are prodromal Parkinson’s disease (PD) features. PD risk prediction models typically dichotomize test results and apply likelihood ratios (LRs) to scores above and below cut-offs. We investigate whe...

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Bibliographic Details
Main Authors: Jonathan P. Bestwick, Stephen D. Auger, Anette E. Schrag, Donald G. Grosset, Sofia Kanavou, Gavin Giovannoni, Andrew J. Lees, Jack Cuzick, Alastair J. Noyce
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/65468704213a42c5a5966766f07c7b64
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