DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons
Transcriptional changes occur in the dorsal root ganglion in response to nerve injury and may contribute to neuropathic pain. Here the authors show that the DNA methyltransferase DNMT3a is upregulated in rodents following nerve injury, and may contribute to pain-like behaviour by decreasing expressi...
Guardado en:
Autores principales: | Jian-Yuan Zhao, Lingli Liang, Xiyao Gu, Zhisong Li, Shaogen Wu, Linlin Sun, Fidelis E. Atianjoh, Jian Feng, Kai Mo, Shushan Jia, Brianna Marie Lutz, Alex Bekker, Eric J. Nestler, Yuan-Xiang Tao |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/6546e90f8d0a479b8916bd70184ce7f5 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Author Correction: DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons
por: Jian-Yuan Zhao, et al.
Publicado: (2020) -
On the evolutionary origin of eukaryotic DNA methyltransferases and Dnmt2.
por: Tomasz P Jurkowski, et al.
Publicado: (2011) -
Histone Methyltransferases SUV39H1 and G9a and DNA Methyltransferase DNMT1 in Penumbra Neurons and Astrocytes after Photothrombotic Stroke
por: Svetlana Sharifulina, et al.
Publicado: (2021) -
DNA Methyltransferase1 (DNMT1) Isoform3 methylates mitochondrial genome and modulates its biology
por: Sunil Kumar Saini, et al.
Publicado: (2017) -
Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3A
por: Young-Chae Kim, et al.
Publicado: (2020)