Transmission-clearance trade-offs indicate that dengue virulence evolution depends on epidemiological context
Theory predicts that pathogens will evolve towards intermediate virulence, yet the necessary trade-offs invoked by this theory have rarely been demonstrated empirically. Here, the authors show that dengue virus dynamics exhibit a trade-off between transmission and clearance rates.
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Main Authors: | Rotem Ben-Shachar, Katia Koelle |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Subjects: | |
Online Access: | https://doaj.org/article/65534d1c53ab449390d58f6025fa28d3 |
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