Ethnobotanical plants used in the management of symptoms of tuberculosis in rural Uganda

Abstract Background Tuberculosis (TB) caused by Mycobacterium tuberculosis is the 13th leading cause of death worldwide. The emergence of multidrug-resistant TB (MDR-TB) poses a major health security threat. Plants have traditionally been used as a source of medicine, since olden days and 80% of the...

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Autores principales:	Christine Oryema, Karlmax Rutaro, Sam William Oyet, Geoffrey Maxwell Malinga
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	TB Treatment Traditional Medicine Knowledge Practitioners Medicinal plants Arctic medicine. Tropical medicine RC955-962
Acceso en línea:	https://doaj.org/article/6554c4ede05e4fd997d0ca51c7b9ff6d
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spelling	oai:doaj.org-article:6554c4ede05e4fd997d0ca51c7b9ff6d2021-11-28T12:39:05ZEthnobotanical plants used in the management of symptoms of tuberculosis in rural Uganda10.1186/s41182-021-00384-21349-4147https://doaj.org/article/6554c4ede05e4fd997d0ca51c7b9ff6d2021-11-01T00:00:00Zhttps://doi.org/10.1186/s41182-021-00384-2https://doaj.org/toc/1349-4147Abstract Background Tuberculosis (TB) caused by Mycobacterium tuberculosis is the 13th leading cause of death worldwide. The emergence of multidrug-resistant TB (MDR-TB) poses a major health security threat. Plants have traditionally been used as a source of medicine, since olden days and 80% of the communities in Africa still rely on herbal medicines for their healthcare. In many parts of Uganda, some plants have shown ethno-pharmacological prospects for the treatment of TB, and yet they have not been fully researched. Aim This study aimed to document plant species used traditionally by the herbalists and non-herbalist communities of Kitgum and Pader districts for managing symptoms of TB. Methods An ethnobotanical study was carried out in 42 randomly selected villages in Kitgum and Pader districts between August 2020 and January 2021. Information was obtained by administering semi-structured questionnaires to 176 respondents identified by snowball and random sampling methods. Data were analysed and presented using descriptive statistics and Informant Consensus Factor (ICF). Results Overall, only 27% of the respondents were knowledgeable about plants used for managing symptoms of TB. Nine plant species belonging to six families (Mimosaceae, Apiaceae, Lamiaceae, Rutaceae, Loganiaceae and Rubiaceae) were used to manage symptoms of TB. The most representative family was Rutaceae with three species, followed by Rubiaceae (two species) and the rest of the families were represented by one species each. The most frequently recorded species were Steganotaenia araliacea Hochst. (8.5%), Gardenia ternifolia Schumach. & Thonn (6.8%) and Albizia adianthifolia (Schum.) W.Wight (6.8%). Most of the medicinal plants were trees, and roots (69%) were the most frequently plant part used, followed by the bark (16%) and leaves (15%). The most common method of preparation was by pounding and mixing concoction with water. The administration of the concoctions was mostly done orally. Conclusions The results established the existence of few medicinal plants for managing symptoms of TB among the Acholi communities which could be used in developing new, effective plant-based antimycobacterial drugs. The few plants mentioned might face conservation threats due to exploitations of the roots. Phytochemical and toxicological studies are recommended to identify active compounds responsible for antimycobacterial activity.Christine OryemaKarlmax RutaroSam William OyetGeoffrey Maxwell MalingaBMCarticleTBTreatmentTraditional MedicineKnowledgePractitionersMedicinal plantsArctic medicine. Tropical medicineRC955-962ENTropical Medicine and Health, Vol 49, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	TB Treatment Traditional Medicine Knowledge Practitioners Medicinal plants Arctic medicine. Tropical medicine RC955-962
spellingShingle	TB Treatment Traditional Medicine Knowledge Practitioners Medicinal plants Arctic medicine. Tropical medicine RC955-962 Christine Oryema Karlmax Rutaro Sam William Oyet Geoffrey Maxwell Malinga Ethnobotanical plants used in the management of symptoms of tuberculosis in rural Uganda
description	Abstract Background Tuberculosis (TB) caused by Mycobacterium tuberculosis is the 13th leading cause of death worldwide. The emergence of multidrug-resistant TB (MDR-TB) poses a major health security threat. Plants have traditionally been used as a source of medicine, since olden days and 80% of the communities in Africa still rely on herbal medicines for their healthcare. In many parts of Uganda, some plants have shown ethno-pharmacological prospects for the treatment of TB, and yet they have not been fully researched. Aim This study aimed to document plant species used traditionally by the herbalists and non-herbalist communities of Kitgum and Pader districts for managing symptoms of TB. Methods An ethnobotanical study was carried out in 42 randomly selected villages in Kitgum and Pader districts between August 2020 and January 2021. Information was obtained by administering semi-structured questionnaires to 176 respondents identified by snowball and random sampling methods. Data were analysed and presented using descriptive statistics and Informant Consensus Factor (ICF). Results Overall, only 27% of the respondents were knowledgeable about plants used for managing symptoms of TB. Nine plant species belonging to six families (Mimosaceae, Apiaceae, Lamiaceae, Rutaceae, Loganiaceae and Rubiaceae) were used to manage symptoms of TB. The most representative family was Rutaceae with three species, followed by Rubiaceae (two species) and the rest of the families were represented by one species each. The most frequently recorded species were Steganotaenia araliacea Hochst. (8.5%), Gardenia ternifolia Schumach. & Thonn (6.8%) and Albizia adianthifolia (Schum.) W.Wight (6.8%). Most of the medicinal plants were trees, and roots (69%) were the most frequently plant part used, followed by the bark (16%) and leaves (15%). The most common method of preparation was by pounding and mixing concoction with water. The administration of the concoctions was mostly done orally. Conclusions The results established the existence of few medicinal plants for managing symptoms of TB among the Acholi communities which could be used in developing new, effective plant-based antimycobacterial drugs. The few plants mentioned might face conservation threats due to exploitations of the roots. Phytochemical and toxicological studies are recommended to identify active compounds responsible for antimycobacterial activity.
format	article
author	Christine Oryema Karlmax Rutaro Sam William Oyet Geoffrey Maxwell Malinga
author_facet	Christine Oryema Karlmax Rutaro Sam William Oyet Geoffrey Maxwell Malinga
author_sort	Christine Oryema
title	Ethnobotanical plants used in the management of symptoms of tuberculosis in rural Uganda
title_short	Ethnobotanical plants used in the management of symptoms of tuberculosis in rural Uganda
title_full	Ethnobotanical plants used in the management of symptoms of tuberculosis in rural Uganda
title_fullStr	Ethnobotanical plants used in the management of symptoms of tuberculosis in rural Uganda
title_full_unstemmed	Ethnobotanical plants used in the management of symptoms of tuberculosis in rural Uganda
title_sort	ethnobotanical plants used in the management of symptoms of tuberculosis in rural uganda
publisher	BMC
publishDate	2021
url	https://doaj.org/article/6554c4ede05e4fd997d0ca51c7b9ff6d
work_keys_str_mv	AT christineoryema ethnobotanicalplantsusedinthemanagementofsymptomsoftuberculosisinruraluganda AT karlmaxrutaro ethnobotanicalplantsusedinthemanagementofsymptomsoftuberculosisinruraluganda AT samwilliamoyet ethnobotanicalplantsusedinthemanagementofsymptomsoftuberculosisinruraluganda AT geoffreymaxwellmalinga ethnobotanicalplantsusedinthemanagementofsymptomsoftuberculosisinruraluganda
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Ethnobotanical plants used in the management of symptoms of tuberculosis in rural Uganda

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