The minimal meningococcal ProQ protein has an intrinsic capacity for structure-based global RNA recognition

The minimal meningococcal ProQ protein has an intrinsic capacity for structure-based global RNA recognition

FinO-domain proteins are bacterial RNA-binding proteins with a wide range of target specificities. Here, the authors employ UV CLIP-seq and show that minimal ProQ protein of Neisseria meningitidis binds to various small non-coding RNAs and mRNAs involved in virulence.

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Autores principales: Saskia Bauriedl, Milan Gerovac, Nadja Heidrich, Thorsten Bischler, Lars Barquist, Jörg Vogel, Christoph Schoen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/655596a4764d4f3a9233202e0aa98712
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spelling oai:doaj.org-article:655596a4764d4f3a9233202e0aa987122021-12-02T15:02:55ZThe minimal meningococcal ProQ protein has an intrinsic capacity for structure-based global RNA recognition10.1038/s41467-020-16650-62041-1723https://doaj.org/article/655596a4764d4f3a9233202e0aa987122020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16650-6https://doaj.org/toc/2041-1723FinO-domain proteins are bacterial RNA-binding proteins with a wide range of target specificities. Here, the authors employ UV CLIP-seq and show that minimal ProQ protein of Neisseria meningitidis binds to various small non-coding RNAs and mRNAs involved in virulence.Saskia BauriedlMilan GerovacNadja HeidrichThorsten BischlerLars BarquistJörg VogelChristoph SchoenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Saskia Bauriedl
Milan Gerovac
Nadja Heidrich
Thorsten Bischler
Lars Barquist
Jörg Vogel
Christoph Schoen
The minimal meningococcal ProQ protein has an intrinsic capacity for structure-based global RNA recognition
description FinO-domain proteins are bacterial RNA-binding proteins with a wide range of target specificities. Here, the authors employ UV CLIP-seq and show that minimal ProQ protein of Neisseria meningitidis binds to various small non-coding RNAs and mRNAs involved in virulence.
format article
author Saskia Bauriedl
Milan Gerovac
Nadja Heidrich
Thorsten Bischler
Lars Barquist
Jörg Vogel
Christoph Schoen
author_facet Saskia Bauriedl
Milan Gerovac
Nadja Heidrich
Thorsten Bischler
Lars Barquist
Jörg Vogel
Christoph Schoen
author_sort Saskia Bauriedl
title The minimal meningococcal ProQ protein has an intrinsic capacity for structure-based global RNA recognition
title_short The minimal meningococcal ProQ protein has an intrinsic capacity for structure-based global RNA recognition
title_full The minimal meningococcal ProQ protein has an intrinsic capacity for structure-based global RNA recognition
title_fullStr The minimal meningococcal ProQ protein has an intrinsic capacity for structure-based global RNA recognition
title_full_unstemmed The minimal meningococcal ProQ protein has an intrinsic capacity for structure-based global RNA recognition
title_sort minimal meningococcal proq protein has an intrinsic capacity for structure-based global rna recognition
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/655596a4764d4f3a9233202e0aa98712
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