Visual field changes as an early indicator of glioblastoma multiforme progression: two cases of functional vision changes before MRI detection

Visual field changes as an early indicator of glioblastoma multiforme progression: two cases of functional vision changes before MRI detection

Kate Xie,1,* Catherine Y Liu,1,* Anton N Hasso,2 Robert Wade Crow1 1Department of Ophthalmology, Gavin Herbert Eye Institute, University of California, Irvine, Irvine, CA, USA, 2Department of Radiological Sciences, University of California Irvine Medical Center, Orange, CA, USA *These authors cont...

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Autores principales: Xie K, Liu CY, Hasso AN, Crow RW
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2015
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Ophthalmology
RE1-994
Acceso en línea:https://doaj.org/article/6561ce1501e54ea395d1c2ec9184d476
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spelling oai:doaj.org-article:6561ce1501e54ea395d1c2ec9184d4762021-12-02T02:37:51ZVisual field changes as an early indicator of glioblastoma multiforme progression: two cases of functional vision changes before MRI detection1177-5483https://doaj.org/article/6561ce1501e54ea395d1c2ec9184d4762015-06-01T00:00:00Zhttp://www.dovepress.com/visual-field-changes-as-an-early-indicator-of-glioblastoma-multiforme--peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Kate Xie,1,* Catherine Y Liu,1,* Anton N Hasso,2 Robert Wade Crow1 1Department of Ophthalmology, Gavin Herbert Eye Institute, University of California, Irvine, Irvine, CA, USA, 2Department of Radiological Sciences, University of California Irvine Medical Center, Orange, CA, USA *These authors contributed equally to this work Abstract: Glioblastoma multiforme is an aggressive tumor associated with a high rate of recurrence even after maximal therapy. In a disease with poor prognosis and rapid deterioration, early detection of tumor progression is necessary to make timely treatment decisions or to initiate end of life care. We identify two cases where Humphrey visual field testing predated magnetic resonance imaging and positron emission tomography findings of tumor progression by months in glioblastoma multiforme. New or worsening visual field defects may indicate signs of tumor progression in glioblastoma multiforme and should prompt further investigation. Keywords: glioblastoma multiforme, optic pathway, visual field defectsXie KLiu CYHasso ANCrow RWDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 1041-1047 (2015)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Xie K
Liu CY
Hasso AN
Crow RW
Visual field changes as an early indicator of glioblastoma multiforme progression: two cases of functional vision changes before MRI detection
description Kate Xie,1,* Catherine Y Liu,1,* Anton N Hasso,2 Robert Wade Crow1 1Department of Ophthalmology, Gavin Herbert Eye Institute, University of California, Irvine, Irvine, CA, USA, 2Department of Radiological Sciences, University of California Irvine Medical Center, Orange, CA, USA *These authors contributed equally to this work Abstract: Glioblastoma multiforme is an aggressive tumor associated with a high rate of recurrence even after maximal therapy. In a disease with poor prognosis and rapid deterioration, early detection of tumor progression is necessary to make timely treatment decisions or to initiate end of life care. We identify two cases where Humphrey visual field testing predated magnetic resonance imaging and positron emission tomography findings of tumor progression by months in glioblastoma multiforme. New or worsening visual field defects may indicate signs of tumor progression in glioblastoma multiforme and should prompt further investigation. Keywords: glioblastoma multiforme, optic pathway, visual field defects
format article
author Xie K
Liu CY
Hasso AN
Crow RW
author_facet Xie K
Liu CY
Hasso AN
Crow RW
author_sort Xie K
title Visual field changes as an early indicator of glioblastoma multiforme progression: two cases of functional vision changes before MRI detection
title_short Visual field changes as an early indicator of glioblastoma multiforme progression: two cases of functional vision changes before MRI detection
title_full Visual field changes as an early indicator of glioblastoma multiforme progression: two cases of functional vision changes before MRI detection
title_fullStr Visual field changes as an early indicator of glioblastoma multiforme progression: two cases of functional vision changes before MRI detection
title_full_unstemmed Visual field changes as an early indicator of glioblastoma multiforme progression: two cases of functional vision changes before MRI detection
title_sort visual field changes as an early indicator of glioblastoma multiforme progression: two cases of functional vision changes before mri detection
publisher Dove Medical Press
publishDate 2015
url https://doaj.org/article/6561ce1501e54ea395d1c2ec9184d476
work_keys_str_mv AT xiek visualfieldchangesasanearlyindicatorofglioblastomamultiformeprogressiontwocasesofnbspfunctionalvisionchangesbeforemridetection
AT liucy visualfieldchangesasanearlyindicatorofglioblastomamultiformeprogressiontwocasesofnbspfunctionalvisionchangesbeforemridetection
AT hassoan visualfieldchangesasanearlyindicatorofglioblastomamultiformeprogressiontwocasesofnbspfunctionalvisionchangesbeforemridetection
AT crowrw visualfieldchangesasanearlyindicatorofglioblastomamultiformeprogressiontwocasesofnbspfunctionalvisionchangesbeforemridetection
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