A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment

Gene drives raise safety concerns around unintended propagation. Here the authors present a trans-complementing split-gene drive that requires inheritance of separate transgenes to assemble a fully functional drive.

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Detalles Bibliográficos
Autores principales: Víctor López Del Amo, Alena L. Bishop, Héctor M. Sánchez C., Jared B. Bennett, Xuechun Feng, John M. Marshall, Ethan Bier, Valentino M. Gantz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/656384f4cb644824ac325eaeb9b29a92
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Descripción
Sumario:Gene drives raise safety concerns around unintended propagation. Here the authors present a trans-complementing split-gene drive that requires inheritance of separate transgenes to assemble a fully functional drive.