A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment

Gene drives raise safety concerns around unintended propagation. Here the authors present a trans-complementing split-gene drive that requires inheritance of separate transgenes to assemble a fully functional drive.

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Detalles Bibliográficos
Autores principales:	Víctor López Del Amo, Alena L. Bishop, Héctor M. Sánchez C., Jared B. Bennett, Xuechun Feng, John M. Marshall, Ethan Bier, Valentino M. Gantz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/656384f4cb644824ac325eaeb9b29a92
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spelling	oai:doaj.org-article:656384f4cb644824ac325eaeb9b29a922021-12-02T17:32:59ZA transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment10.1038/s41467-019-13977-72041-1723https://doaj.org/article/656384f4cb644824ac325eaeb9b29a922020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13977-7https://doaj.org/toc/2041-1723Gene drives raise safety concerns around unintended propagation. Here the authors present a trans-complementing split-gene drive that requires inheritance of separate transgenes to assemble a fully functional drive.Víctor López Del AmoAlena L. BishopHéctor M. Sánchez C.Jared B. BennettXuechun FengJohn M. MarshallEthan BierValentino M. GantzNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Víctor López Del Amo Alena L. Bishop Héctor M. Sánchez C. Jared B. Bennett Xuechun Feng John M. Marshall Ethan Bier Valentino M. Gantz A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment
description	Gene drives raise safety concerns around unintended propagation. Here the authors present a trans-complementing split-gene drive that requires inheritance of separate transgenes to assemble a fully functional drive.
format	article
author	Víctor López Del Amo Alena L. Bishop Héctor M. Sánchez C. Jared B. Bennett Xuechun Feng John M. Marshall Ethan Bier Valentino M. Gantz
author_facet	Víctor López Del Amo Alena L. Bishop Héctor M. Sánchez C. Jared B. Bennett Xuechun Feng John M. Marshall Ethan Bier Valentino M. Gantz
author_sort	Víctor López Del Amo
title	A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment
title_short	A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment
title_full	A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment
title_fullStr	A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment
title_full_unstemmed	A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment
title_sort	transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/656384f4cb644824ac325eaeb9b29a92
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A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment

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