An infection-induced RhoB-Beclin 1-Hsp90 complex enhances clearance of uropathogenic Escherichia coli

An infection-induced RhoB-Beclin 1-Hsp90 complex enhances clearance of uropathogenic Escherichia coli

Bacterial invasion can lead to multiple host cell responses. Here, the authors show that in a model of uropathogenic E. coli, RhoB is upregulated and induces autophagosome formation in a complex with Beclin1 and Hsp90, promoting bacterial clearance.

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Detalles Bibliográficos
Autores principales: Chunhui Miao, Mingyu Yu, Geng Pei, Zhenyi Ma, Lisong Zhang, Jianming Yang, Junqiang Lv, Zhi-Song Zhang, Evan T. Keller, Zhi Yao, Quan Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
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Acceso en línea:https://doaj.org/article/6566a1096e0b4b0b8b6e482feb14534a
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