Immunization with pre-erythrocytic antigen CelTOS from Plasmodium falciparum elicits cross-species protection against heterologous challenge with Plasmodium berghei.

Immunization with pre-erythrocytic antigen CelTOS from Plasmodium falciparum elicits cross-species protection against heterologous challenge with Plasmodium berghei.

<h4>Background</h4>The Plasmodium protein Cell-traversal protein for ookinetes and sporozoites (CelTOS) plays an important role in cell traversal of host cells in both, mosquito and vertebrates, and is required for successful malaria infections. CelTOS is highly conserved among the Plasm...

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Autores principales: Elke S Bergmann-Leitner, Ryan M Mease, Patricia De La Vega, Tatyana Savranskaya, Mark Polhemus, Christian Ockenhouse, Evelina Angov
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/657518e76283467787c73792401c1705
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