Cell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo

Post transcriptional modification of RNAs represents an important layer of gene regulation. Here the authors describe NAIL-MS—a method for monoisotopic RNA labeling in cell culture—demonstrating its capabilities by analyzing the modification kinetics of total tRNA, 18S rRNA and tRNAPhe as models....

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Matthias Heiss, Felix Hagelskamp, Virginie Marchand, Yuri Motorin, Stefanie Kellner
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6576875b198b477bb54b337f7ff87c65
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6576875b198b477bb54b337f7ff87c65
record_format	dspace
spelling	oai:doaj.org-article:6576875b198b477bb54b337f7ff87c652021-12-02T14:12:04ZCell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo10.1038/s41467-020-20576-42041-1723https://doaj.org/article/6576875b198b477bb54b337f7ff87c652021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20576-4https://doaj.org/toc/2041-1723Post transcriptional modification of RNAs represents an important layer of gene regulation. Here the authors describe NAIL-MS—a method for monoisotopic RNA labeling in cell culture—demonstrating its capabilities by analyzing the modification kinetics of total tRNA, 18S rRNA and tRNAPhe as models.Matthias HeissFelix HagelskampVirginie MarchandYuri MotorinStefanie KellnerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Matthias Heiss Felix Hagelskamp Virginie Marchand Yuri Motorin Stefanie Kellner Cell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo
description	Post transcriptional modification of RNAs represents an important layer of gene regulation. Here the authors describe NAIL-MS—a method for monoisotopic RNA labeling in cell culture—demonstrating its capabilities by analyzing the modification kinetics of total tRNA, 18S rRNA and tRNAPhe as models.
format	article
author	Matthias Heiss Felix Hagelskamp Virginie Marchand Yuri Motorin Stefanie Kellner
author_facet	Matthias Heiss Felix Hagelskamp Virginie Marchand Yuri Motorin Stefanie Kellner
author_sort	Matthias Heiss
title	Cell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo
title_short	Cell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo
title_full	Cell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo
title_fullStr	Cell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo
title_full_unstemmed	Cell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo
title_sort	cell culture nail-ms allows insight into human trna and rrna modification dynamics in vivo
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6576875b198b477bb54b337f7ff87c65
work_keys_str_mv	AT matthiasheiss cellculturenailmsallowsinsightintohumantrnaandrrnamodificationdynamicsinvivo AT felixhagelskamp cellculturenailmsallowsinsightintohumantrnaandrrnamodificationdynamicsinvivo AT virginiemarchand cellculturenailmsallowsinsightintohumantrnaandrrnamodificationdynamicsinvivo AT yurimotorin cellculturenailmsallowsinsightintohumantrnaandrrnamodificationdynamicsinvivo AT stefaniekellner cellculturenailmsallowsinsightintohumantrnaandrrnamodificationdynamicsinvivo
_version_	1718391846017695744

Cell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo

Ejemplares similares