Cell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo
Post transcriptional modification of RNAs represents an important layer of gene regulation. Here the authors describe NAIL-MS—a method for monoisotopic RNA labeling in cell culture—demonstrating its capabilities by analyzing the modification kinetics of total tRNA, 18S rRNA and tRNAPhe as models....
Guardado en:
Autores principales: | Matthias Heiss, Felix Hagelskamp, Virginie Marchand, Yuri Motorin, Stefanie Kellner |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/6576875b198b477bb54b337f7ff87c65 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Time-resolved NMR monitoring of tRNA maturation
por: Pierre Barraud, et al.
Publicado: (2019) -
Partial methylation at Am100 in 18S rRNA of baker's yeast reveals ribosome heterogeneity on the level of eukaryotic rRNA modification.
por: Markus Buchhaupt, et al.
Publicado: (2014) -
NAIL-MS reveals the repair of 2-methylthiocytidine by AlkB in E. coli
por: Valentin F. Reichle, et al.
Publicado: (2019) -
Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control
por: Jin-Yu Yang, et al.
Publicado: (2018) -
Chimeric design of pyrrolysyl-tRNA synthetase/tRNA pairs and canonical synthetase/tRNA pairs for genetic code expansion
por: Wenlong Ding, et al.
Publicado: (2020)