N-octanoyl dopamine inhibits the expression of a subset of κB regulated genes: potential role of p65 Ser276 phosphorylation.

N-octanoyl dopamine inhibits the expression of a subset of κB regulated genes: potential role of p65 Ser276 phosphorylation.

<h4>Background and purpose</h4>Catechol containing compounds have anti-inflammatory properties, yet for catecholamines these properties are modest. Since we have previously demonstrated that the synthetic dopamine derivative N-octanoyl dopamine (NOD) has superior anti-inflammatory proper...

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Main Authors: Maximilia C Hottenrott, Johannes Wedel, Sophie Gaertner, Eleni Stamellou, Tineke Kraaij, Linda Mandel, Ralf Loesel, Carsten Sticht, Simone Hoeger, Lamia Ait-Hsiko, Angelika Schedel, Mathias Hafner, Benito Yard, Charalambos Tsagogiorgas
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/65788b7d3f5d42a0b68082d001b8a47a
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