Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast

Asynchronicity in fungal spore germination makes transcriptomic analysis of the process challenging. Here, the authors assay single cell transcriptomes of germinating yeast cells and find that one of the histone H3 genes shows fluctuating expression, disruption of which causes germination defects.

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Autores principales: Hayato Tsuyuzaki, Masahito Hosokawa, Koji Arikawa, Takuya Yoda, Naoyuki Okada, Haruko Takeyama, Masamitsu Sato
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/658c9b12092e4c3f8d4e63e3deb0a930
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spelling oai:doaj.org-article:658c9b12092e4c3f8d4e63e3deb0a9302021-12-02T15:39:17ZTime-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast10.1038/s41467-020-15060-y2041-1723https://doaj.org/article/658c9b12092e4c3f8d4e63e3deb0a9302020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15060-yhttps://doaj.org/toc/2041-1723Asynchronicity in fungal spore germination makes transcriptomic analysis of the process challenging. Here, the authors assay single cell transcriptomes of germinating yeast cells and find that one of the histone H3 genes shows fluctuating expression, disruption of which causes germination defects.Hayato TsuyuzakiMasahito HosokawaKoji ArikawaTakuya YodaNaoyuki OkadaHaruko TakeyamaMasamitsu SatoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hayato Tsuyuzaki
Masahito Hosokawa
Koji Arikawa
Takuya Yoda
Naoyuki Okada
Haruko Takeyama
Masamitsu Sato
Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast
description Asynchronicity in fungal spore germination makes transcriptomic analysis of the process challenging. Here, the authors assay single cell transcriptomes of germinating yeast cells and find that one of the histone H3 genes shows fluctuating expression, disruption of which causes germination defects.
format article
author Hayato Tsuyuzaki
Masahito Hosokawa
Koji Arikawa
Takuya Yoda
Naoyuki Okada
Haruko Takeyama
Masamitsu Sato
author_facet Hayato Tsuyuzaki
Masahito Hosokawa
Koji Arikawa
Takuya Yoda
Naoyuki Okada
Haruko Takeyama
Masamitsu Sato
author_sort Hayato Tsuyuzaki
title Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast
title_short Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast
title_full Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast
title_fullStr Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast
title_full_unstemmed Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast
title_sort time-lapse single-cell transcriptomics reveals modulation of histone h3 for dormancy breaking in fission yeast
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/658c9b12092e4c3f8d4e63e3deb0a930
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