Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast
Asynchronicity in fungal spore germination makes transcriptomic analysis of the process challenging. Here, the authors assay single cell transcriptomes of germinating yeast cells and find that one of the histone H3 genes shows fluctuating expression, disruption of which causes germination defects.
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Nature Portfolio
2020
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oai:doaj.org-article:658c9b12092e4c3f8d4e63e3deb0a9302021-12-02T15:39:17ZTime-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast10.1038/s41467-020-15060-y2041-1723https://doaj.org/article/658c9b12092e4c3f8d4e63e3deb0a9302020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15060-yhttps://doaj.org/toc/2041-1723Asynchronicity in fungal spore germination makes transcriptomic analysis of the process challenging. Here, the authors assay single cell transcriptomes of germinating yeast cells and find that one of the histone H3 genes shows fluctuating expression, disruption of which causes germination defects.Hayato TsuyuzakiMasahito HosokawaKoji ArikawaTakuya YodaNaoyuki OkadaHaruko TakeyamaMasamitsu SatoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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Science Q Hayato Tsuyuzaki Masahito Hosokawa Koji Arikawa Takuya Yoda Naoyuki Okada Haruko Takeyama Masamitsu Sato Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast |
description |
Asynchronicity in fungal spore germination makes transcriptomic analysis of the process challenging. Here, the authors assay single cell transcriptomes of germinating yeast cells and find that one of the histone H3 genes shows fluctuating expression, disruption of which causes germination defects. |
format |
article |
author |
Hayato Tsuyuzaki Masahito Hosokawa Koji Arikawa Takuya Yoda Naoyuki Okada Haruko Takeyama Masamitsu Sato |
author_facet |
Hayato Tsuyuzaki Masahito Hosokawa Koji Arikawa Takuya Yoda Naoyuki Okada Haruko Takeyama Masamitsu Sato |
author_sort |
Hayato Tsuyuzaki |
title |
Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast |
title_short |
Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast |
title_full |
Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast |
title_fullStr |
Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast |
title_full_unstemmed |
Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast |
title_sort |
time-lapse single-cell transcriptomics reveals modulation of histone h3 for dormancy breaking in fission yeast |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/658c9b12092e4c3f8d4e63e3deb0a930 |
work_keys_str_mv |
AT hayatotsuyuzaki timelapsesinglecelltranscriptomicsrevealsmodulationofhistoneh3fordormancybreakinginfissionyeast AT masahitohosokawa timelapsesinglecelltranscriptomicsrevealsmodulationofhistoneh3fordormancybreakinginfissionyeast AT kojiarikawa timelapsesinglecelltranscriptomicsrevealsmodulationofhistoneh3fordormancybreakinginfissionyeast AT takuyayoda timelapsesinglecelltranscriptomicsrevealsmodulationofhistoneh3fordormancybreakinginfissionyeast AT naoyukiokada timelapsesinglecelltranscriptomicsrevealsmodulationofhistoneh3fordormancybreakinginfissionyeast AT harukotakeyama timelapsesinglecelltranscriptomicsrevealsmodulationofhistoneh3fordormancybreakinginfissionyeast AT masamitsusato timelapsesinglecelltranscriptomicsrevealsmodulationofhistoneh3fordormancybreakinginfissionyeast |
_version_ |
1718385936030498816 |