MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling

TRIM proteins are known to play critical roles in the context of viral infection. Here the authors establish MG53 (TRIM72) suppresses IFN and inflammation by modulation of ryanodine receptor related intracellular calcium induction.

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Autores principales:	Matthew Sermersheim, Adam D. Kenney, Pei-Hui Lin, Temet M. McMichael, Chuanxi Cai, Kristyn Gumpper, T. M. Ayodele Adesanya, Haichang Li, Xinyu Zhou, Ki-Ho Park, Jacob S. Yount, Jianjie Ma
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6597955c13bc4dd2bb5688a5b442a740
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spelling	oai:doaj.org-article:6597955c13bc4dd2bb5688a5b442a7402021-12-02T16:08:14ZMG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling10.1038/s41467-020-17177-62041-1723https://doaj.org/article/6597955c13bc4dd2bb5688a5b442a7402020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17177-6https://doaj.org/toc/2041-1723TRIM proteins are known to play critical roles in the context of viral infection. Here the authors establish MG53 (TRIM72) suppresses IFN and inflammation by modulation of ryanodine receptor related intracellular calcium induction.Matthew SermersheimAdam D. KenneyPei-Hui LinTemet M. McMichaelChuanxi CaiKristyn GumpperT. M. Ayodele AdesanyaHaichang LiXinyu ZhouKi-Ho ParkJacob S. YountJianjie MaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Matthew Sermersheim Adam D. Kenney Pei-Hui Lin Temet M. McMichael Chuanxi Cai Kristyn Gumpper T. M. Ayodele Adesanya Haichang Li Xinyu Zhou Ki-Ho Park Jacob S. Yount Jianjie Ma MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
description	TRIM proteins are known to play critical roles in the context of viral infection. Here the authors establish MG53 (TRIM72) suppresses IFN and inflammation by modulation of ryanodine receptor related intracellular calcium induction.
format	article
author	Matthew Sermersheim Adam D. Kenney Pei-Hui Lin Temet M. McMichael Chuanxi Cai Kristyn Gumpper T. M. Ayodele Adesanya Haichang Li Xinyu Zhou Ki-Ho Park Jacob S. Yount Jianjie Ma
author_facet	Matthew Sermersheim Adam D. Kenney Pei-Hui Lin Temet M. McMichael Chuanxi Cai Kristyn Gumpper T. M. Ayodele Adesanya Haichang Li Xinyu Zhou Ki-Ho Park Jacob S. Yount Jianjie Ma
author_sort	Matthew Sermersheim
title	MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
title_short	MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
title_full	MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
title_fullStr	MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
title_full_unstemmed	MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
title_sort	mg53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/6597955c13bc4dd2bb5688a5b442a740
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MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling

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