Quality of life in patients with stable coronary artery disease submitted to percutaneous, surgical, and medical therapies: a cohort study

Abstract Background Clinical, surgical, and percutaneous strategies similarly prevent major cardiovascular events in patients with stable coronary artery disease (CAD). The possibility that these strategies have differential effects on health-related quality of life (HRQoL) has been debated, particu...

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Autores principales: Lucas Molinari Veloso da Silveira, Adriana Silveira Almeida, Felipe C. Fuchs, Aline Gonçalves Silva, Marcelo Balbinot Lucca, Samuel Scopel, Sandra C. Fuchs, Flávio D. Fuchs
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Publicado: BMC 2021
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spelling oai:doaj.org-article:6597bf8f852d469698e67a2cb2c88b932021-11-28T12:25:22ZQuality of life in patients with stable coronary artery disease submitted to percutaneous, surgical, and medical therapies: a cohort study10.1186/s12955-021-01886-71477-7525https://doaj.org/article/6597bf8f852d469698e67a2cb2c88b932021-11-01T00:00:00Zhttps://doi.org/10.1186/s12955-021-01886-7https://doaj.org/toc/1477-7525Abstract Background Clinical, surgical, and percutaneous strategies similarly prevent major cardiovascular events in patients with stable coronary artery disease (CAD). The possibility that these strategies have differential effects on health-related quality of life (HRQoL) has been debated, particularly in patients treated outside clinical trials. Methods We assigned 454 patients diagnosed with CAD during an elective diagnostic coronary angiography to coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), or optimal medical treatment (OMT), and followed them for an average of 5.2 ± 1.5 years. HRQoL was assessed using a validated Brazilian version of the 12-Item Short-Form Health Survey questionnaire. The association between therapeutic strategies and quality of life scores was tested using variance analysis and adjusted for confounders in a general linear model. Results There were no differences in the mental component summary scores in the follow-up evaluation by therapeutic strategies: 51.4, 53.7, and 52.3 for OMT, PCI, and CABG, respectively. Physical component summary scores were higher in the PCI group than the CABG and OMT groups (46.4 vs. 42.9 and 43.8, respectively); however, these differences were no longer different after adjustment for confounding variables. Conclusion In a long-term follow-up of patients with stable CAD, HRQoL did not differ in patients treated by medical, percutaneous, or surgical treatments.Lucas Molinari Veloso da SilveiraAdriana Silveira AlmeidaFelipe C. FuchsAline Gonçalves SilvaMarcelo Balbinot LuccaSamuel ScopelSandra C. FuchsFlávio D. FuchsBMCarticleCardiac surgeryPercutaneous coronary interventionStable coronary artery diseaseQuality of lifeCohort studyComputer applications to medicine. Medical informaticsR858-859.7ENHealth and Quality of Life Outcomes, Vol 19, Iss 1, Pp 1-7 (2021)
institution DOAJ
collection DOAJ
language EN
topic Cardiac surgery
Percutaneous coronary intervention
Stable coronary artery disease
Quality of life
Cohort study
Computer applications to medicine. Medical informatics
R858-859.7
spellingShingle Cardiac surgery
Percutaneous coronary intervention
Stable coronary artery disease
Quality of life
Cohort study
Computer applications to medicine. Medical informatics
R858-859.7
Lucas Molinari Veloso da Silveira
Adriana Silveira Almeida
Felipe C. Fuchs
Aline Gonçalves Silva
Marcelo Balbinot Lucca
Samuel Scopel
Sandra C. Fuchs
Flávio D. Fuchs
Quality of life in patients with stable coronary artery disease submitted to percutaneous, surgical, and medical therapies: a cohort study
description Abstract Background Clinical, surgical, and percutaneous strategies similarly prevent major cardiovascular events in patients with stable coronary artery disease (CAD). The possibility that these strategies have differential effects on health-related quality of life (HRQoL) has been debated, particularly in patients treated outside clinical trials. Methods We assigned 454 patients diagnosed with CAD during an elective diagnostic coronary angiography to coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), or optimal medical treatment (OMT), and followed them for an average of 5.2 ± 1.5 years. HRQoL was assessed using a validated Brazilian version of the 12-Item Short-Form Health Survey questionnaire. The association between therapeutic strategies and quality of life scores was tested using variance analysis and adjusted for confounders in a general linear model. Results There were no differences in the mental component summary scores in the follow-up evaluation by therapeutic strategies: 51.4, 53.7, and 52.3 for OMT, PCI, and CABG, respectively. Physical component summary scores were higher in the PCI group than the CABG and OMT groups (46.4 vs. 42.9 and 43.8, respectively); however, these differences were no longer different after adjustment for confounding variables. Conclusion In a long-term follow-up of patients with stable CAD, HRQoL did not differ in patients treated by medical, percutaneous, or surgical treatments.
format article
author Lucas Molinari Veloso da Silveira
Adriana Silveira Almeida
Felipe C. Fuchs
Aline Gonçalves Silva
Marcelo Balbinot Lucca
Samuel Scopel
Sandra C. Fuchs
Flávio D. Fuchs
author_facet Lucas Molinari Veloso da Silveira
Adriana Silveira Almeida
Felipe C. Fuchs
Aline Gonçalves Silva
Marcelo Balbinot Lucca
Samuel Scopel
Sandra C. Fuchs
Flávio D. Fuchs
author_sort Lucas Molinari Veloso da Silveira
title Quality of life in patients with stable coronary artery disease submitted to percutaneous, surgical, and medical therapies: a cohort study
title_short Quality of life in patients with stable coronary artery disease submitted to percutaneous, surgical, and medical therapies: a cohort study
title_full Quality of life in patients with stable coronary artery disease submitted to percutaneous, surgical, and medical therapies: a cohort study
title_fullStr Quality of life in patients with stable coronary artery disease submitted to percutaneous, surgical, and medical therapies: a cohort study
title_full_unstemmed Quality of life in patients with stable coronary artery disease submitted to percutaneous, surgical, and medical therapies: a cohort study
title_sort quality of life in patients with stable coronary artery disease submitted to percutaneous, surgical, and medical therapies: a cohort study
publisher BMC
publishDate 2021
url https://doaj.org/article/6597bf8f852d469698e67a2cb2c88b93
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