Gene synthesis allows biologists to source genes from farther away in the tree of life

Gene synthesis has expanded the ability to modify and create DNA sequences, with implications for biosurveillance. The authors use machine learning and codon theory to identify synthetic genes in Addgene data, and show that synthesis accelerates human-directed gene transfer across the tree of life.

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Autores principales:	Aditya M. Kunjapur, Philipp Pfingstag, Neil C. Thompson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/659835cf92cb405fa24b7ea079e16c67
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spelling	oai:doaj.org-article:659835cf92cb405fa24b7ea079e16c672021-12-02T15:34:40ZGene synthesis allows biologists to source genes from farther away in the tree of life10.1038/s41467-018-06798-72041-1723https://doaj.org/article/659835cf92cb405fa24b7ea079e16c672018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06798-7https://doaj.org/toc/2041-1723Gene synthesis has expanded the ability to modify and create DNA sequences, with implications for biosurveillance. The authors use machine learning and codon theory to identify synthetic genes in Addgene data, and show that synthesis accelerates human-directed gene transfer across the tree of life.Aditya M. KunjapurPhilipp PfingstagNeil C. ThompsonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Aditya M. Kunjapur Philipp Pfingstag Neil C. Thompson Gene synthesis allows biologists to source genes from farther away in the tree of life
description	Gene synthesis has expanded the ability to modify and create DNA sequences, with implications for biosurveillance. The authors use machine learning and codon theory to identify synthetic genes in Addgene data, and show that synthesis accelerates human-directed gene transfer across the tree of life.
format	article
author	Aditya M. Kunjapur Philipp Pfingstag Neil C. Thompson
author_facet	Aditya M. Kunjapur Philipp Pfingstag Neil C. Thompson
author_sort	Aditya M. Kunjapur
title	Gene synthesis allows biologists to source genes from farther away in the tree of life
title_short	Gene synthesis allows biologists to source genes from farther away in the tree of life
title_full	Gene synthesis allows biologists to source genes from farther away in the tree of life
title_fullStr	Gene synthesis allows biologists to source genes from farther away in the tree of life
title_full_unstemmed	Gene synthesis allows biologists to source genes from farther away in the tree of life
title_sort	gene synthesis allows biologists to source genes from farther away in the tree of life
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/659835cf92cb405fa24b7ea079e16c67
work_keys_str_mv	AT adityamkunjapur genesynthesisallowsbiologiststosourcegenesfromfartherawayinthetreeoflife AT philipppfingstag genesynthesisallowsbiologiststosourcegenesfromfartherawayinthetreeoflife AT neilcthompson genesynthesisallowsbiologiststosourcegenesfromfartherawayinthetreeoflife
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Gene synthesis allows biologists to source genes from farther away in the tree of life

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