ORAL ALLERGY SYNDROME

Abstract. Oral allergy syndrome (OAS) is defined as a set of clinical manifestations caused by IgE-mediated allergic  reactions  that  occur  at  oral  and  pharyngeal  mucosae  in  the  patients  with  pollen  sensitization  after ingestion of certain fruits, vegetables, nuts and spices. OAS arises...

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Autores principales: A. V. Sergeev, M. A. Mokronosova
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Lenguaje:RU
Publicado: SPb RAACI 2014
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spelling oai:doaj.org-article:65c15aa379a44250aca37332c586b94d2021-11-18T08:03:40ZORAL ALLERGY SYNDROME1563-06252313-741X10.15789/1563-0625-2011-1-17-28https://doaj.org/article/65c15aa379a44250aca37332c586b94d2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/411https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Oral allergy syndrome (OAS) is defined as a set of clinical manifestations caused by IgE-mediated allergic  reactions  that  occur  at  oral  and  pharyngeal  mucosae  in  the  patients  with  pollen  sensitization  after ingestion of certain fruits, vegetables, nuts and spices. OAS arises from cross-reactivity between specific pollen and food allergens, due to similarity of a configuration and amino acid sequence of allergenic molecules. OAS is considered as class II food allergy, being caused by thermo- and chemolabile allergens, and it is rarely combined with generalized manifestations of food allergy. Prevalence and spectrum of the causal allergens depend on a kind of pollen sensitization. In Moscow region, as well as in Northern Europe, allergic sensitization most commonly occurs to the pollen of leaf trees, whereas OAS is mostly connected with ingestion of fruits from Rosaceae family and nuts. Since last years, a newly developed technique of component-resolved molecular diagnosis (CR diagnostics) allows of more precise detection of OAS-causing allergen molecules. These data are of extreme importance for administration of adequate nutritional therapy and prediction of SIT efficiency. (Med. Immunol., 2011, vol. 13, N 1, pp 17-28)A. V. SergeevM. A. MokronosovaSPb RAACIarticlepollinosis, oral allergy syndrome, cr-diagnosisImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 13, Iss 1, Pp 17-28 (2014)
institution DOAJ
collection DOAJ
language RU
topic pollinosis, oral allergy syndrome, cr-diagnosis
Immunologic diseases. Allergy
RC581-607
spellingShingle pollinosis, oral allergy syndrome, cr-diagnosis
Immunologic diseases. Allergy
RC581-607
A. V. Sergeev
M. A. Mokronosova
ORAL ALLERGY SYNDROME
description Abstract. Oral allergy syndrome (OAS) is defined as a set of clinical manifestations caused by IgE-mediated allergic  reactions  that  occur  at  oral  and  pharyngeal  mucosae  in  the  patients  with  pollen  sensitization  after ingestion of certain fruits, vegetables, nuts and spices. OAS arises from cross-reactivity between specific pollen and food allergens, due to similarity of a configuration and amino acid sequence of allergenic molecules. OAS is considered as class II food allergy, being caused by thermo- and chemolabile allergens, and it is rarely combined with generalized manifestations of food allergy. Prevalence and spectrum of the causal allergens depend on a kind of pollen sensitization. In Moscow region, as well as in Northern Europe, allergic sensitization most commonly occurs to the pollen of leaf trees, whereas OAS is mostly connected with ingestion of fruits from Rosaceae family and nuts. Since last years, a newly developed technique of component-resolved molecular diagnosis (CR diagnostics) allows of more precise detection of OAS-causing allergen molecules. These data are of extreme importance for administration of adequate nutritional therapy and prediction of SIT efficiency. (Med. Immunol., 2011, vol. 13, N 1, pp 17-28)
format article
author A. V. Sergeev
M. A. Mokronosova
author_facet A. V. Sergeev
M. A. Mokronosova
author_sort A. V. Sergeev
title ORAL ALLERGY SYNDROME
title_short ORAL ALLERGY SYNDROME
title_full ORAL ALLERGY SYNDROME
title_fullStr ORAL ALLERGY SYNDROME
title_full_unstemmed ORAL ALLERGY SYNDROME
title_sort oral allergy syndrome
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/65c15aa379a44250aca37332c586b94d
work_keys_str_mv AT avsergeev oralallergysyndrome
AT mamokronosova oralallergysyndrome
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