The practical utility of genetic screening in school settings

Abstract Can genetic screening be used to personalize education for students? Genome-wide association studies (GWAS) screen an individual’s DNA for specific variations in their genome, and how said variations relate to specific traits. The variations can then be assigned a corresponding weight and s...

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Autores principales:	J. Shero, W. van Dijk, A. Edwards, C. Schatschneider, E. J. Solari, S. A. Hart
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Special aspects of education LC8-6691 Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Acceso en línea:	https://doaj.org/article/65cac04c13594aa5a6d2ffc5e0dc1b19
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spelling	oai:doaj.org-article:65cac04c13594aa5a6d2ffc5e0dc1b192021-12-02T15:56:55ZThe practical utility of genetic screening in school settings10.1038/s41539-021-00090-y2056-7936https://doaj.org/article/65cac04c13594aa5a6d2ffc5e0dc1b192021-06-01T00:00:00Zhttps://doi.org/10.1038/s41539-021-00090-yhttps://doaj.org/toc/2056-7936Abstract Can genetic screening be used to personalize education for students? Genome-wide association studies (GWAS) screen an individual’s DNA for specific variations in their genome, and how said variations relate to specific traits. The variations can then be assigned a corresponding weight and summed to produce polygenic scores (PGS) for given traits. Though first developed for disease risk, PGS is now used to predict educational achievement. Using a novel simulation method, this paper examines if PGS could advance screening in schools, a goal of personalized education. Results show limited potential benefits for using PGS to personalize education for individual students. However, further analysis shows PGS can be effectively used alongside progress monitoring measures to screen for learning disability risk. Altogether, PGS is not useful in personalizing education for every child but has potential utility when used simultaneously with additional screening tools to help determine which children may struggle academically.J. SheroW. van DijkA. EdwardsC. SchatschneiderE. J. SolariS. A. HartNature PortfolioarticleSpecial aspects of educationLC8-6691Neurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENnpj Science of Learning, Vol 6, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Special aspects of education LC8-6691 Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
spellingShingle	Special aspects of education LC8-6691 Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 J. Shero W. van Dijk A. Edwards C. Schatschneider E. J. Solari S. A. Hart The practical utility of genetic screening in school settings
description	Abstract Can genetic screening be used to personalize education for students? Genome-wide association studies (GWAS) screen an individual’s DNA for specific variations in their genome, and how said variations relate to specific traits. The variations can then be assigned a corresponding weight and summed to produce polygenic scores (PGS) for given traits. Though first developed for disease risk, PGS is now used to predict educational achievement. Using a novel simulation method, this paper examines if PGS could advance screening in schools, a goal of personalized education. Results show limited potential benefits for using PGS to personalize education for individual students. However, further analysis shows PGS can be effectively used alongside progress monitoring measures to screen for learning disability risk. Altogether, PGS is not useful in personalizing education for every child but has potential utility when used simultaneously with additional screening tools to help determine which children may struggle academically.
format	article
author	J. Shero W. van Dijk A. Edwards C. Schatschneider E. J. Solari S. A. Hart
author_facet	J. Shero W. van Dijk A. Edwards C. Schatschneider E. J. Solari S. A. Hart
author_sort	J. Shero
title	The practical utility of genetic screening in school settings
title_short	The practical utility of genetic screening in school settings
title_full	The practical utility of genetic screening in school settings
title_fullStr	The practical utility of genetic screening in school settings
title_full_unstemmed	The practical utility of genetic screening in school settings
title_sort	practical utility of genetic screening in school settings
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/65cac04c13594aa5a6d2ffc5e0dc1b19
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The practical utility of genetic screening in school settings

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