Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry

The endoplasmic reticulum membrane protein complex (EMC) is known to play a role in SV40 viral infection but precise mechanisms are unclear. Here, the authors report that the EMC acts as tether of late endosome–endoplasmic reticulum interorganellar membrane contact sites to promote SV40 viral infect...

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Main Authors:	Parikshit Bagchi, Mauricio Torres, Ling Qi, Billy Tsai
Format:	article
Language:	EN
Published:	Nature Portfolio 2020
Subjects:	Science Q
Online Access:	https://doaj.org/article/65f39b7ff7a54d2399d6e7184374128b
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spelling	oai:doaj.org-article:65f39b7ff7a54d2399d6e7184374128b2021-12-02T17:33:15ZSelective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry10.1038/s41467-020-14967-w2041-1723https://doaj.org/article/65f39b7ff7a54d2399d6e7184374128b2020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14967-whttps://doaj.org/toc/2041-1723The endoplasmic reticulum membrane protein complex (EMC) is known to play a role in SV40 viral infection but precise mechanisms are unclear. Here, the authors report that the EMC acts as tether of late endosome–endoplasmic reticulum interorganellar membrane contact sites to promote SV40 viral infection.Parikshit BagchiMauricio TorresLing QiBilly TsaiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Parikshit Bagchi Mauricio Torres Ling Qi Billy Tsai Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry
description	The endoplasmic reticulum membrane protein complex (EMC) is known to play a role in SV40 viral infection but precise mechanisms are unclear. Here, the authors report that the EMC acts as tether of late endosome–endoplasmic reticulum interorganellar membrane contact sites to promote SV40 viral infection.
format	article
author	Parikshit Bagchi Mauricio Torres Ling Qi Billy Tsai
author_facet	Parikshit Bagchi Mauricio Torres Ling Qi Billy Tsai
author_sort	Parikshit Bagchi
title	Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry
title_short	Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry
title_full	Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry
title_fullStr	Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry
title_full_unstemmed	Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry
title_sort	selective emc subunits act as molecular tethers of intracellular organelles exploited during viral entry
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/65f39b7ff7a54d2399d6e7184374128b
work_keys_str_mv	AT parikshitbagchi selectiveemcsubunitsactasmoleculartethersofintracellularorganellesexploitedduringviralentry AT mauriciotorres selectiveemcsubunitsactasmoleculartethersofintracellularorganellesexploitedduringviralentry AT lingqi selectiveemcsubunitsactasmoleculartethersofintracellularorganellesexploitedduringviralentry AT billytsai selectiveemcsubunitsactasmoleculartethersofintracellularorganellesexploitedduringviralentry
_version_	1718380004078780416

Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry

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