Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry

The endoplasmic reticulum membrane protein complex (EMC) is known to play a role in SV40 viral infection but precise mechanisms are unclear. Here, the authors report that the EMC acts as tether of late endosome–endoplasmic reticulum interorganellar membrane contact sites to promote SV40 viral infect...

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Autores principales: Parikshit Bagchi, Mauricio Torres, Ling Qi, Billy Tsai
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/65f39b7ff7a54d2399d6e7184374128b
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spelling oai:doaj.org-article:65f39b7ff7a54d2399d6e7184374128b2021-12-02T17:33:15ZSelective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry10.1038/s41467-020-14967-w2041-1723https://doaj.org/article/65f39b7ff7a54d2399d6e7184374128b2020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14967-whttps://doaj.org/toc/2041-1723The endoplasmic reticulum membrane protein complex (EMC) is known to play a role in SV40 viral infection but precise mechanisms are unclear. Here, the authors report that the EMC acts as tether of late endosome–endoplasmic reticulum interorganellar membrane contact sites to promote SV40 viral infection.Parikshit BagchiMauricio TorresLing QiBilly TsaiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Parikshit Bagchi
Mauricio Torres
Ling Qi
Billy Tsai
Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry
description The endoplasmic reticulum membrane protein complex (EMC) is known to play a role in SV40 viral infection but precise mechanisms are unclear. Here, the authors report that the EMC acts as tether of late endosome–endoplasmic reticulum interorganellar membrane contact sites to promote SV40 viral infection.
format article
author Parikshit Bagchi
Mauricio Torres
Ling Qi
Billy Tsai
author_facet Parikshit Bagchi
Mauricio Torres
Ling Qi
Billy Tsai
author_sort Parikshit Bagchi
title Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry
title_short Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry
title_full Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry
title_fullStr Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry
title_full_unstemmed Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry
title_sort selective emc subunits act as molecular tethers of intracellular organelles exploited during viral entry
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/65f39b7ff7a54d2399d6e7184374128b
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AT mauriciotorres selectiveemcsubunitsactasmoleculartethersofintracellularorganellesexploitedduringviralentry
AT lingqi selectiveemcsubunitsactasmoleculartethersofintracellularorganellesexploitedduringviralentry
AT billytsai selectiveemcsubunitsactasmoleculartethersofintracellularorganellesexploitedduringviralentry
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