Stromal Claudin14-heterozygosity, but not deletion, increases tumour blood leakage without affecting tumour growth.
The maintenance of endothelial cell-cell junctions is vital for the control of blood vessel leakage and is known to be important in the growth and maturation of new blood vessels during angiogenesis. Here we have investigated the role of a tight junction molecule, Claudin 14, in tumour blood vessel...
Guardado en:
Autores principales: | Marianne Baker, Louise E Reynolds, Stephen D Robinson, Delphine M Lees, Maddy Parsons, George Elia, Kairbaan Hodivala-Dilke |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
|
Materias: | |
Acceso en línea: | https://doaj.org/article/65ff3c9f977a4399ac2c953da2c108a7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth
por: Tanguy Lechertier, et al.
Publicado: (2020) -
Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors
por: Jiqiu Cheng, et al.
Publicado: (2017) -
SDHC epi-mutation testing in gastrointestinal stromal tumours and related tumours in clinical practice
por: Ruth T. Casey, et al.
Publicado: (2019) -
Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors
por: Jiqiu Cheng, et al.
Publicado: (2019) -
Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors
por: Jiqiu Cheng, et al.
Publicado: (2018)