Stromal Claudin14-heterozygosity, but not deletion, increases tumour blood leakage without affecting tumour growth.
The maintenance of endothelial cell-cell junctions is vital for the control of blood vessel leakage and is known to be important in the growth and maturation of new blood vessels during angiogenesis. Here we have investigated the role of a tight junction molecule, Claudin 14, in tumour blood vessel...
Enregistré dans:
Auteurs principaux: | Marianne Baker, Louise E Reynolds, Stephen D Robinson, Delphine M Lees, Maddy Parsons, George Elia, Kairbaan Hodivala-Dilke |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/65ff3c9f977a4399ac2c953da2c108a7 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth
par: Tanguy Lechertier, et autres
Publié: (2020) -
Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors
par: Jiqiu Cheng, et autres
Publié: (2017) -
SDHC epi-mutation testing in gastrointestinal stromal tumours and related tumours in clinical practice
par: Ruth T. Casey, et autres
Publié: (2019) -
Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors
par: Jiqiu Cheng, et autres
Publié: (2019) -
Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors
par: Jiqiu Cheng, et autres
Publié: (2018)