Intravitreal Methotrexate
Abstract Intravitreal methotrexate (MTX) has been proven to be an effective treatment for various intraocular diseases. In this article, a comprehensive review was performed on intravitreal applications of methotrexate. Different aspects of the administration of intravitreal MTX for various clinical...
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Knowledge E
2021
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oai:doaj.org-article:66076d5f78874c49b217fc5ae7b99c342021-11-09T08:05:35ZIntravitreal Methotrexate2008-20102008-322X10.18502/jovr.v16i4.9756https://doaj.org/article/66076d5f78874c49b217fc5ae7b99c342021-10-01T00:00:00Zhttps://doi.org/10.18502/jovr.v16i4.9756https://doaj.org/toc/2008-2010https://doaj.org/toc/2008-322XAbstract Intravitreal methotrexate (MTX) has been proven to be an effective treatment for various intraocular diseases. In this article, a comprehensive review was performed on intravitreal applications of methotrexate. Different aspects of the administration of intravitreal MTX for various clinical conditions such as intraocular tumors, proliferative vitreoretinopathy, diabetic retinopathy, age-related macular degeneration, and uveitis were reviewed and the adverse effects of intravitreal injection of MTX were discussed. The most common indications are intraocular lymphoma and uveitis. Other applications remain challenging and more studies are needed to establish the role of intravitreal MTX in the management of ocular diseases.Fatemeh AbdiS. Saeed MohammadiKhalil Ghasemi FalavarjaniKnowledge Earticleinflammationintraocular tumorintravitreal injectionmethotrexateproliferative vitreretinopathyuveitisOphthalmologyRE1-994ENJournal of Ophthalmic & Vision Research, Vol 16, Iss 4, Pp 657-669 (2021) |
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DOAJ |
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DOAJ |
| language |
EN |
| topic |
inflammation intraocular tumor intravitreal injection methotrexate proliferative vitreretinopathy uveitis Ophthalmology RE1-994 |
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inflammation intraocular tumor intravitreal injection methotrexate proliferative vitreretinopathy uveitis Ophthalmology RE1-994 Fatemeh Abdi S. Saeed Mohammadi Khalil Ghasemi Falavarjani Intravitreal Methotrexate |
| description |
Abstract Intravitreal methotrexate (MTX) has been proven to be an effective treatment for various intraocular diseases. In this article, a comprehensive review was performed on intravitreal applications of methotrexate. Different aspects of the administration of intravitreal MTX for various clinical conditions such as intraocular tumors, proliferative vitreoretinopathy, diabetic retinopathy, age-related macular degeneration, and uveitis were reviewed and the adverse effects of intravitreal injection of MTX were discussed. The most common indications are intraocular lymphoma and uveitis. Other applications remain challenging and more studies are needed to establish the role of intravitreal MTX in the management of ocular diseases. |
| format |
article |
| author |
Fatemeh Abdi S. Saeed Mohammadi Khalil Ghasemi Falavarjani |
| author_facet |
Fatemeh Abdi S. Saeed Mohammadi Khalil Ghasemi Falavarjani |
| author_sort |
Fatemeh Abdi |
| title |
Intravitreal Methotrexate |
| title_short |
Intravitreal Methotrexate |
| title_full |
Intravitreal Methotrexate |
| title_fullStr |
Intravitreal Methotrexate |
| title_full_unstemmed |
Intravitreal Methotrexate |
| title_sort |
intravitreal methotrexate |
| publisher |
Knowledge E |
| publishDate |
2021 |
| url |
https://doaj.org/article/66076d5f78874c49b217fc5ae7b99c34 |
| work_keys_str_mv |
AT fatemehabdi intravitrealmethotrexate AT ssaeedmohammadi intravitrealmethotrexate AT khalilghasemifalavarjani intravitrealmethotrexate |
| _version_ |
1718441203038420992 |