Quantitative analysis of protein-protein interactions and post-translational modifications in rare immune populations

Rare immune or stem cell populations are difficult to quantitatively analyze for protein-protein interactions or post-translational modifications despite advances in proteomics. Here the authors develop proximity ligation imaging cytometry for high-resolution detection at a single cell level.

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Bibliographic Details
Main Authors: Ayelet Avin, Maayan Levy, Ziv Porat, Jakub Abramson
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Q
Online Access:https://doaj.org/article/6610bc4b09e243d2a3a4ca662bb17a50
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Summary:Rare immune or stem cell populations are difficult to quantitatively analyze for protein-protein interactions or post-translational modifications despite advances in proteomics. Here the authors develop proximity ligation imaging cytometry for high-resolution detection at a single cell level.