Pharmaceutical recommendations in a university hospital transplant unit

Introduction: The transplanted patient has a complex pharmacotherapy, with the pharmacist having an important role in the multidisciplinary team. Objective: To analyze the pharmaceutical recommendations made during the hospitalization of the patients in kidney and liver transplant units. Methods: T...

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Autores principales: Maria K. Pinheiro, Elana F. Chaves, Alene B. Oliveira, Cinthya C. Andrade, Katherine X. Bastos, Marjorie M. Guedes
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PT
Publicado: Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde 2020
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Acceso en línea:https://doaj.org/article/66111f75b57b40bfb799a2167df53fbe
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spelling oai:doaj.org-article:66111f75b57b40bfb799a2167df53fbe2021-11-28T02:46:06ZPharmaceutical recommendations in a university hospital transplant unit10.30968/rbfhss.2019.104.03612179-59242316-7750https://doaj.org/article/66111f75b57b40bfb799a2167df53fbe2020-03-01T00:00:00Zhttps://www.rbfhss.org.br/sbrafh/article/view/361https://doaj.org/toc/2179-5924https://doaj.org/toc/2316-7750 Introduction: The transplanted patient has a complex pharmacotherapy, with the pharmacist having an important role in the multidisciplinary team. Objective: To analyze the pharmaceutical recommendations made during the hospitalization of the patients in kidney and liver transplant units. Methods: This was a cross-sectional study in which pharmaceutical recommendations from May 2017 to April 2018 were collected from the records contained in the database of the Clinical Pharmacy Unit of a University Hospital in Fortaleza, Brazil. The recommendations were categorized and analyzed based on the classification used in the institution. Results: There were 1241 pharmaceutical recommendations involving 325 patients and 1466 medications. The recommendations were more frequent during liver transplantation (54.2%, n = 672), with dose adjustments (18.2%, n = 122) and dilution / reconstitution (9.8%, n = 66) being the most predominant types. In kidney transplantation, recommendations for education about medication use (17.6%, n = 100) and treatment adherence strategies (17.6%, n = 100) were the most predominant. The most frequent therapeutic classes were systemic antibacterials (31.2%, n = 458) and immunosuppressants (25.1%, n = 368). The acceptance rate of recommendations for kidney and liver transplantation were 95.1% (n = 541) and 95.4% (n = 641), respectively. Conclusions: The present study showed a high frequency of pharmaceutical recommendations and these results demonstrate that the detection of drug-related problems generates pharmaceutical recommendations that can contribute to the reduction of negative drug-associated results and increase patient safety. Maria K. PinheiroElana F. ChavesAlene B. OliveiraCinthya C. AndradeKatherine X. BastosMarjorie M. GuedesSociedade Brasileira de Farmácia Hospitalar e Serviços de SaúdearticlePublic aspects of medicineRA1-1270Pharmacy and materia medicaRS1-441Therapeutics. PharmacologyRM1-950ENPTRevista Brasileira de Farmácia Hospitalar e Serviços de Saúde, Vol 10, Iss 4 (2020)
institution DOAJ
collection DOAJ
language EN
PT
topic Public aspects of medicine
RA1-1270
Pharmacy and materia medica
RS1-441
Therapeutics. Pharmacology
RM1-950
spellingShingle Public aspects of medicine
RA1-1270
Pharmacy and materia medica
RS1-441
Therapeutics. Pharmacology
RM1-950
Maria K. Pinheiro
Elana F. Chaves
Alene B. Oliveira
Cinthya C. Andrade
Katherine X. Bastos
Marjorie M. Guedes
Pharmaceutical recommendations in a university hospital transplant unit
description Introduction: The transplanted patient has a complex pharmacotherapy, with the pharmacist having an important role in the multidisciplinary team. Objective: To analyze the pharmaceutical recommendations made during the hospitalization of the patients in kidney and liver transplant units. Methods: This was a cross-sectional study in which pharmaceutical recommendations from May 2017 to April 2018 were collected from the records contained in the database of the Clinical Pharmacy Unit of a University Hospital in Fortaleza, Brazil. The recommendations were categorized and analyzed based on the classification used in the institution. Results: There were 1241 pharmaceutical recommendations involving 325 patients and 1466 medications. The recommendations were more frequent during liver transplantation (54.2%, n = 672), with dose adjustments (18.2%, n = 122) and dilution / reconstitution (9.8%, n = 66) being the most predominant types. In kidney transplantation, recommendations for education about medication use (17.6%, n = 100) and treatment adherence strategies (17.6%, n = 100) were the most predominant. The most frequent therapeutic classes were systemic antibacterials (31.2%, n = 458) and immunosuppressants (25.1%, n = 368). The acceptance rate of recommendations for kidney and liver transplantation were 95.1% (n = 541) and 95.4% (n = 641), respectively. Conclusions: The present study showed a high frequency of pharmaceutical recommendations and these results demonstrate that the detection of drug-related problems generates pharmaceutical recommendations that can contribute to the reduction of negative drug-associated results and increase patient safety.
format article
author Maria K. Pinheiro
Elana F. Chaves
Alene B. Oliveira
Cinthya C. Andrade
Katherine X. Bastos
Marjorie M. Guedes
author_facet Maria K. Pinheiro
Elana F. Chaves
Alene B. Oliveira
Cinthya C. Andrade
Katherine X. Bastos
Marjorie M. Guedes
author_sort Maria K. Pinheiro
title Pharmaceutical recommendations in a university hospital transplant unit
title_short Pharmaceutical recommendations in a university hospital transplant unit
title_full Pharmaceutical recommendations in a university hospital transplant unit
title_fullStr Pharmaceutical recommendations in a university hospital transplant unit
title_full_unstemmed Pharmaceutical recommendations in a university hospital transplant unit
title_sort pharmaceutical recommendations in a university hospital transplant unit
publisher Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde
publishDate 2020
url https://doaj.org/article/66111f75b57b40bfb799a2167df53fbe
work_keys_str_mv AT mariakpinheiro pharmaceuticalrecommendationsinauniversityhospitaltransplantunit
AT elanafchaves pharmaceuticalrecommendationsinauniversityhospitaltransplantunit
AT aleneboliveira pharmaceuticalrecommendationsinauniversityhospitaltransplantunit
AT cinthyacandrade pharmaceuticalrecommendationsinauniversityhospitaltransplantunit
AT katherinexbastos pharmaceuticalrecommendationsinauniversityhospitaltransplantunit
AT marjoriemguedes pharmaceuticalrecommendationsinauniversityhospitaltransplantunit
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