Engineered macrophages as near-infrared light activated drug vectors for chemo-photodynamic therapy of primary and bone metastatic breast cancer

Engineered macrophages as near-infrared light activated drug vectors for chemo-photodynamic therapy of primary and bone metastatic breast cancer

Bone metastases are associated with poor prognosis in patients with breast cancer and limited therapeutic options. Here the authors exploit near-infrared light responsive macrophages for the tumor-selective delivery of oxaliplatin prodrug for chemo-photodynamic therapy of primary and bone metastatic...

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Autores principales: Yanjuan Huang, Zilin Guan, Xiuling Dai, Yifeng Shen, Qin Wei, Lingling Ren, Jingwen Jiang, Zhanghong Xiao, Yali Jiang, Di Liu, Zeqian Huang, Xiaoyu Xu, Yong Luo, Chunshun Zhao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6612050fe360461b84661984dadfcace
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spelling oai:doaj.org-article:6612050fe360461b84661984dadfcace2021-12-02T18:36:59ZEngineered macrophages as near-infrared light activated drug vectors for chemo-photodynamic therapy of primary and bone metastatic breast cancer10.1038/s41467-021-24564-02041-1723https://doaj.org/article/6612050fe360461b84661984dadfcace2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24564-0https://doaj.org/toc/2041-1723Bone metastases are associated with poor prognosis in patients with breast cancer and limited therapeutic options. Here the authors exploit near-infrared light responsive macrophages for the tumor-selective delivery of oxaliplatin prodrug for chemo-photodynamic therapy of primary and bone metastatic breast cancer.Yanjuan HuangZilin GuanXiuling DaiYifeng ShenQin WeiLingling RenJingwen JiangZhanghong XiaoYali JiangDi LiuZeqian HuangXiaoyu XuYong LuoChunshun ZhaoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yanjuan Huang
Zilin Guan
Xiuling Dai
Yifeng Shen
Qin Wei
Lingling Ren
Jingwen Jiang
Zhanghong Xiao
Yali Jiang
Di Liu
Zeqian Huang
Xiaoyu Xu
Yong Luo
Chunshun Zhao
Engineered macrophages as near-infrared light activated drug vectors for chemo-photodynamic therapy of primary and bone metastatic breast cancer
description Bone metastases are associated with poor prognosis in patients with breast cancer and limited therapeutic options. Here the authors exploit near-infrared light responsive macrophages for the tumor-selective delivery of oxaliplatin prodrug for chemo-photodynamic therapy of primary and bone metastatic breast cancer.
format article
author Yanjuan Huang
Zilin Guan
Xiuling Dai
Yifeng Shen
Qin Wei
Lingling Ren
Jingwen Jiang
Zhanghong Xiao
Yali Jiang
Di Liu
Zeqian Huang
Xiaoyu Xu
Yong Luo
Chunshun Zhao
author_facet Yanjuan Huang
Zilin Guan
Xiuling Dai
Yifeng Shen
Qin Wei
Lingling Ren
Jingwen Jiang
Zhanghong Xiao
Yali Jiang
Di Liu
Zeqian Huang
Xiaoyu Xu
Yong Luo
Chunshun Zhao
author_sort Yanjuan Huang
title Engineered macrophages as near-infrared light activated drug vectors for chemo-photodynamic therapy of primary and bone metastatic breast cancer
title_short Engineered macrophages as near-infrared light activated drug vectors for chemo-photodynamic therapy of primary and bone metastatic breast cancer
title_full Engineered macrophages as near-infrared light activated drug vectors for chemo-photodynamic therapy of primary and bone metastatic breast cancer
title_fullStr Engineered macrophages as near-infrared light activated drug vectors for chemo-photodynamic therapy of primary and bone metastatic breast cancer
title_full_unstemmed Engineered macrophages as near-infrared light activated drug vectors for chemo-photodynamic therapy of primary and bone metastatic breast cancer
title_sort engineered macrophages as near-infrared light activated drug vectors for chemo-photodynamic therapy of primary and bone metastatic breast cancer
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/6612050fe360461b84661984dadfcace
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