The Role of Immune Microenvironment in Maxillofacial Bone Homeostasis
Maxillofacial bone defects are common medical problems caused by congenital defects, necrosis, trauma, tumor, inflammation, and fractures non-union. Maxillofacial bone defects often need bone graft, which has many difficulties, such as limited autogenous bone supply and donor site morbidity. Bone ti...
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Frontiers Media S.A.
2021
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oai:doaj.org-article:66151edef0f14bce9bea9e314975e3d62021-12-01T11:47:08ZThe Role of Immune Microenvironment in Maxillofacial Bone Homeostasis2673-491510.3389/fdmed.2021.780973https://doaj.org/article/66151edef0f14bce9bea9e314975e3d62021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fdmed.2021.780973/fullhttps://doaj.org/toc/2673-4915Maxillofacial bone defects are common medical problems caused by congenital defects, necrosis, trauma, tumor, inflammation, and fractures non-union. Maxillofacial bone defects often need bone graft, which has many difficulties, such as limited autogenous bone supply and donor site morbidity. Bone tissue engineering is a promising strategy to overcome the above-mentioned problems. Osteoimmunology is the inter-discipline that focuses on the relationship between the skeletal and immune systems. The immune microenvironment plays a crucial role in bone healing, tissue repair and regeneration in maxillofacial region. Recent studies have revealed the vital role of immune microenvironment and bone homeostasis. In this study, we analyzed the complex interaction between immune microenvironment and bone regeneration process in oral and maxillofacial region, which will be important to improve the clinical outcome of the bone injury treatment.Na LiNa LiLin FuLin FuZehan LiZehan LiYue KeYue KeYanqiu WangYanqiu WangJintao WuJintao WuJinhua YuJinhua YuFrontiers Media S.A.articleimmune microenvironmentbone homeostasisosteoimmunologycytokinesimmune cells (ICs)DentistryRK1-715ENFrontiers in Dental Medicine, Vol 2 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
immune microenvironment bone homeostasis osteoimmunology cytokines immune cells (ICs) Dentistry RK1-715 |
| spellingShingle |
immune microenvironment bone homeostasis osteoimmunology cytokines immune cells (ICs) Dentistry RK1-715 Na Li Na Li Lin Fu Lin Fu Zehan Li Zehan Li Yue Ke Yue Ke Yanqiu Wang Yanqiu Wang Jintao Wu Jintao Wu Jinhua Yu Jinhua Yu The Role of Immune Microenvironment in Maxillofacial Bone Homeostasis |
| description |
Maxillofacial bone defects are common medical problems caused by congenital defects, necrosis, trauma, tumor, inflammation, and fractures non-union. Maxillofacial bone defects often need bone graft, which has many difficulties, such as limited autogenous bone supply and donor site morbidity. Bone tissue engineering is a promising strategy to overcome the above-mentioned problems. Osteoimmunology is the inter-discipline that focuses on the relationship between the skeletal and immune systems. The immune microenvironment plays a crucial role in bone healing, tissue repair and regeneration in maxillofacial region. Recent studies have revealed the vital role of immune microenvironment and bone homeostasis. In this study, we analyzed the complex interaction between immune microenvironment and bone regeneration process in oral and maxillofacial region, which will be important to improve the clinical outcome of the bone injury treatment. |
| format |
article |
| author |
Na Li Na Li Lin Fu Lin Fu Zehan Li Zehan Li Yue Ke Yue Ke Yanqiu Wang Yanqiu Wang Jintao Wu Jintao Wu Jinhua Yu Jinhua Yu |
| author_facet |
Na Li Na Li Lin Fu Lin Fu Zehan Li Zehan Li Yue Ke Yue Ke Yanqiu Wang Yanqiu Wang Jintao Wu Jintao Wu Jinhua Yu Jinhua Yu |
| author_sort |
Na Li |
| title |
The Role of Immune Microenvironment in Maxillofacial Bone Homeostasis |
| title_short |
The Role of Immune Microenvironment in Maxillofacial Bone Homeostasis |
| title_full |
The Role of Immune Microenvironment in Maxillofacial Bone Homeostasis |
| title_fullStr |
The Role of Immune Microenvironment in Maxillofacial Bone Homeostasis |
| title_full_unstemmed |
The Role of Immune Microenvironment in Maxillofacial Bone Homeostasis |
| title_sort |
role of immune microenvironment in maxillofacial bone homeostasis |
| publisher |
Frontiers Media S.A. |
| publishDate |
2021 |
| url |
https://doaj.org/article/66151edef0f14bce9bea9e314975e3d6 |
| work_keys_str_mv |
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