Computational design of new Peptide inhibitors for amyloid Beta (aβ) aggregation in Alzheimer's disease: application of a novel methodology.
Alzheimer's disease is the most common form of dementia. It is a neurodegenerative and incurable disease that is associated with the tight packing of amyloid fibrils. This packing is facilitated by the compatibility of the ridges and grooves on the amyloid surface. The GxMxG motif is the major...
Guardado en:
Autores principales: | Gözde Eskici, Mert Gur |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
|
Materias: | |
Acceso en línea: | https://doaj.org/article/66201b7b33f74fcf9dc37cb4952362a3 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Effective screen for amyloid β aggregation inhibitor using amyloid β-conjugated gold nanoparticles
por: Sun-Ho Han, et al.
Publicado: (2010) -
Shedding Light on Alzheimer’s β-Amyloidosis: Photosensitized Methylene Blue Inhibits Self-Assembly of β-Amyloid Peptides and Disintegrates Their Aggregates
por: Byung Il Lee, et al.
Publicado: (2017) -
The nickel-chelator dimethylglyoxime inhibits human amyloid beta peptide in vitro aggregation
por: Stéphane L. Benoit, et al.
Publicado: (2021) -
Publisher Correction: Crocus-derived compounds alter the aggregation pathway of Alzheimer’s Disease - associated beta amyloid protein
por: Nikolaos Stavros Koulakiotis, et al.
Publicado: (2021) -
A Rationally Designed Humanized Antibody Selective for Amyloid Beta Oligomers in Alzheimer’s Disease
por: Ebrima Gibbs, et al.
Publicado: (2019)