The effect of intradialytic exercise on inflammatory markers in hemodialysis patients

Abstract Background Chronic low-grade inflammation is a feature of chronic kidney disease associated with increased risk of multiple morbidities and mortalities. Hemodialysis (HD) patients lead a sedentary life style which may aggravate their inflammatory state and practicing exercise may improve th...

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Autores principales:	Howaida Abdelhameed Elshinnawy, Mahmoud Mohamed Fayez, Dina Abou Bakr Farrag, Moustafa Abd Elnassier AbdElgawad
Formato:	article
Lenguaje:	EN
Publicado:	SpringerOpen 2021
Materias:	Intradialytic exercise Hemodialysis CRP IL-6 Albumin Diseases of the musculoskeletal system RC925-935
Acceso en línea:	https://doaj.org/article/66227f323b7841b0b75dc822f3e12691
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spelling	oai:doaj.org-article:66227f323b7841b0b75dc822f3e126912021-12-05T12:07:53ZThe effect of intradialytic exercise on inflammatory markers in hemodialysis patients10.1186/s43166-021-00084-z1110-161X2090-3235https://doaj.org/article/66227f323b7841b0b75dc822f3e126912021-11-01T00:00:00Zhttps://doi.org/10.1186/s43166-021-00084-zhttps://doaj.org/toc/1110-161Xhttps://doaj.org/toc/2090-3235Abstract Background Chronic low-grade inflammation is a feature of chronic kidney disease associated with increased risk of multiple morbidities and mortalities. Hemodialysis (HD) patients lead a sedentary life style which may aggravate their inflammatory state and practicing exercise may improve this condition. The aim of this work was to study the effect of intradialytic exercise (IDE) on inflammatory markers in HD patients. Results This prospective cohort study included 40 HD patients, divided into 2 groups: exercise group completed IDE for 3 months and non-exercise group matched in age and sex as controls. At baseline, there was no difference between both groups regarding physical performance assessed using short physical performance battery test (SPBT) or inflammatory markers C-reactive protein (CRP) and interleukin 6 (IL-6) P > 0.05. After 3 months, SPBT significantly improved in exercise group (P < 0.001). Also, both serum CRP and IL-6 levels showed significant decrease in exercise group compared to baseline (P < 0.001), while no similar change was noticed in non-exercise group. Conclusions Regular intradialytic aerobic exercise program can improve physical function and inflammation in hemodialysis patients. Further studies on larger number of patients are warranted.Howaida Abdelhameed ElshinnawyMahmoud Mohamed FayezDina Abou Bakr FarragMoustafa Abd Elnassier AbdElgawadSpringerOpenarticleIntradialytic exerciseHemodialysisCRPIL-6AlbuminDiseases of the musculoskeletal systemRC925-935ENEgyptian Rheumatology and Rehabilitation, Vol 48, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Intradialytic exercise Hemodialysis CRP IL-6 Albumin Diseases of the musculoskeletal system RC925-935
spellingShingle	Intradialytic exercise Hemodialysis CRP IL-6 Albumin Diseases of the musculoskeletal system RC925-935 Howaida Abdelhameed Elshinnawy Mahmoud Mohamed Fayez Dina Abou Bakr Farrag Moustafa Abd Elnassier AbdElgawad The effect of intradialytic exercise on inflammatory markers in hemodialysis patients
description	Abstract Background Chronic low-grade inflammation is a feature of chronic kidney disease associated with increased risk of multiple morbidities and mortalities. Hemodialysis (HD) patients lead a sedentary life style which may aggravate their inflammatory state and practicing exercise may improve this condition. The aim of this work was to study the effect of intradialytic exercise (IDE) on inflammatory markers in HD patients. Results This prospective cohort study included 40 HD patients, divided into 2 groups: exercise group completed IDE for 3 months and non-exercise group matched in age and sex as controls. At baseline, there was no difference between both groups regarding physical performance assessed using short physical performance battery test (SPBT) or inflammatory markers C-reactive protein (CRP) and interleukin 6 (IL-6) P > 0.05. After 3 months, SPBT significantly improved in exercise group (P < 0.001). Also, both serum CRP and IL-6 levels showed significant decrease in exercise group compared to baseline (P < 0.001), while no similar change was noticed in non-exercise group. Conclusions Regular intradialytic aerobic exercise program can improve physical function and inflammation in hemodialysis patients. Further studies on larger number of patients are warranted.
format	article
author	Howaida Abdelhameed Elshinnawy Mahmoud Mohamed Fayez Dina Abou Bakr Farrag Moustafa Abd Elnassier AbdElgawad
author_facet	Howaida Abdelhameed Elshinnawy Mahmoud Mohamed Fayez Dina Abou Bakr Farrag Moustafa Abd Elnassier AbdElgawad
author_sort	Howaida Abdelhameed Elshinnawy
title	The effect of intradialytic exercise on inflammatory markers in hemodialysis patients
title_short	The effect of intradialytic exercise on inflammatory markers in hemodialysis patients
title_full	The effect of intradialytic exercise on inflammatory markers in hemodialysis patients
title_fullStr	The effect of intradialytic exercise on inflammatory markers in hemodialysis patients
title_full_unstemmed	The effect of intradialytic exercise on inflammatory markers in hemodialysis patients
title_sort	effect of intradialytic exercise on inflammatory markers in hemodialysis patients
publisher	SpringerOpen
publishDate	2021
url	https://doaj.org/article/66227f323b7841b0b75dc822f3e12691
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The effect of intradialytic exercise on inflammatory markers in hemodialysis patients

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