A generic mechanism of emergence of amyloid protofilaments from disordered oligomeric aggregates.

The presence of oligomeric aggregates, which is often observed during the process of amyloid formation, has recently attracted much attention because it has been associated with a range of neurodegenerative conditions including Alzheimer's and Parkinson's diseases. We provide a description...

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Autores principales: Stefan Auer, Filip Meersman, Christopher M Dobson, Michele Vendruscolo
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
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Acceso en línea:https://doaj.org/article/6636c0f4164943c39dd866bfd1611f45
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