Mortality associated factors in patients with multiorgan dysfunction síndrome

Introduction: multiorgan dysfunction syndrome is characterized by the development of a progressive and potentially reversible physiological dysfunction in two or more organs induced by a wide variety of aggresive situations. The immune-inflammatory system plays an indispensable role in its pathogene...

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Autores principales:	Oláis Machado-Mato, Heidy Rego-Avila, Ariel Delgado-Rodríguez, Adrián Alejandro Vitón-Castillo
Formato:	article
Lenguaje:	ES
Publicado:	Centro Editorial Ciencias Médicas: CPICM Guantánamo 2021
Materias:	insuficiencia multiorgánica choque procesos patológicos puntuaciones en la disfunción de órganos Medicine R
Acceso en línea:	https://doaj.org/article/664b0b33e2af4388bf4166828e1dc35b
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spelling	oai:doaj.org-article:664b0b33e2af4388bf4166828e1dc35b2021-12-01T01:47:10ZMortality associated factors in patients with multiorgan dysfunction síndrome1028-9933https://doaj.org/article/664b0b33e2af4388bf4166828e1dc35b2021-11-01T00:00:00Zhttp://www.revinfcientifica.sld.cu/index.php/ric/article/view/3595https://doaj.org/toc/1028-9933Introduction: multiorgan dysfunction syndrome is characterized by the development of a progressive and potentially reversible physiological dysfunction in two or more organs induced by a wide variety of aggresive situations. The immune-inflammatory system plays an indispensable role in its pathogenesis. Objective: to identify the mortality-associated factors in patients with multiorgan dysfunction syndrome. Method: an analytical, observational, and retrospective cohort study was developed in 68 patients with multiorgan dysfunction syndrome attended in the Intensive Care Medicine Service at the Hospital General Docente "Abel Santamaría Cuadrado", Pinar del Río, between 2018 and 2019. Variables used: age, sex, diagnosis at admission, nutritional assessment, score accordind to Sequential Organ Failure Assessment (SOFA), complications arose, systems and number of organs in failing process. Results: male patients (60.3%) and age group between 60 and 79 (47.06%) were predominant. There was statistically significant association (p<0.05) between SOFA score and the number of failing organs at discharge. Respiratory complications were reported in 36% of deceased patients and in 38.89% of those discharged alive. Patients with cardiovascular failure were the most common (77.94%). Respiratory failure (p<0.001, OR:9 CI:2.52-32.08) and SOFA ≥ 16 (p<0.042, OR:8.76 CI:1.07-71.51) increased the risk of decease-related discharge. Conclusions: excessive body mass index and obesity, admission shock, high score of SOFA, respiratory and nerveous failure, as well as the enormeus failure of organs were associated with the worsen prognoses and with the highest probability of decease.Oláis Machado-MatoHeidy Rego-AvilaAriel Delgado-RodríguezAdrián Alejandro Vitón-CastilloCentro Editorial Ciencias Médicas: CPICM Guantánamoarticleinsuficiencia multiorgánicachoqueprocesos patológicospuntuaciones en la disfunción de órganosMedicineRESRevista Información Científica, Vol 100, Iss 6, Pp e3595-e3595 (2021)
institution	DOAJ
collection	DOAJ
language	ES
topic	insuficiencia multiorgánica choque procesos patológicos puntuaciones en la disfunción de órganos Medicine R
spellingShingle	insuficiencia multiorgánica choque procesos patológicos puntuaciones en la disfunción de órganos Medicine R Oláis Machado-Mato Heidy Rego-Avila Ariel Delgado-Rodríguez Adrián Alejandro Vitón-Castillo Mortality associated factors in patients with multiorgan dysfunction síndrome
description	Introduction: multiorgan dysfunction syndrome is characterized by the development of a progressive and potentially reversible physiological dysfunction in two or more organs induced by a wide variety of aggresive situations. The immune-inflammatory system plays an indispensable role in its pathogenesis. Objective: to identify the mortality-associated factors in patients with multiorgan dysfunction syndrome. Method: an analytical, observational, and retrospective cohort study was developed in 68 patients with multiorgan dysfunction syndrome attended in the Intensive Care Medicine Service at the Hospital General Docente "Abel Santamaría Cuadrado", Pinar del Río, between 2018 and 2019. Variables used: age, sex, diagnosis at admission, nutritional assessment, score accordind to Sequential Organ Failure Assessment (SOFA), complications arose, systems and number of organs in failing process. Results: male patients (60.3%) and age group between 60 and 79 (47.06%) were predominant. There was statistically significant association (p<0.05) between SOFA score and the number of failing organs at discharge. Respiratory complications were reported in 36% of deceased patients and in 38.89% of those discharged alive. Patients with cardiovascular failure were the most common (77.94%). Respiratory failure (p<0.001, OR:9 CI:2.52-32.08) and SOFA ≥ 16 (p<0.042, OR:8.76 CI:1.07-71.51) increased the risk of decease-related discharge. Conclusions: excessive body mass index and obesity, admission shock, high score of SOFA, respiratory and nerveous failure, as well as the enormeus failure of organs were associated with the worsen prognoses and with the highest probability of decease.
format	article
author	Oláis Machado-Mato Heidy Rego-Avila Ariel Delgado-Rodríguez Adrián Alejandro Vitón-Castillo
author_facet	Oláis Machado-Mato Heidy Rego-Avila Ariel Delgado-Rodríguez Adrián Alejandro Vitón-Castillo
author_sort	Oláis Machado-Mato
title	Mortality associated factors in patients with multiorgan dysfunction síndrome
title_short	Mortality associated factors in patients with multiorgan dysfunction síndrome
title_full	Mortality associated factors in patients with multiorgan dysfunction síndrome
title_fullStr	Mortality associated factors in patients with multiorgan dysfunction síndrome
title_full_unstemmed	Mortality associated factors in patients with multiorgan dysfunction síndrome
title_sort	mortality associated factors in patients with multiorgan dysfunction síndrome
publisher	Centro Editorial Ciencias Médicas: CPICM Guantánamo
publishDate	2021
url	https://doaj.org/article/664b0b33e2af4388bf4166828e1dc35b
work_keys_str_mv	AT olaismachadomato mortalityassociatedfactorsinpatientswithmultiorgandysfunctionsindrome AT heidyregoavila mortalityassociatedfactorsinpatientswithmultiorgandysfunctionsindrome AT arieldelgadorodriguez mortalityassociatedfactorsinpatientswithmultiorgandysfunctionsindrome AT adrianalejandrovitoncastillo mortalityassociatedfactorsinpatientswithmultiorgandysfunctionsindrome
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Mortality associated factors in patients with multiorgan dysfunction síndrome

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