Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma

Olfactory neuroblastoma (ONB) is a rare malignant tumor whose genetic basis is poorly understood. Here the authors identify recurrent deletions involving dystrophin in the majority of ONB patient tumors examined.

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Autores principales: Gary L. Gallia, Ming Zhang, Yi Ning, Michael C. Haffner, Denise Batista, Zev A. Binder, Justin A. Bishop, Christine L. Hann, Ralph H. Hruban, Masaru Ishii, Alison P. Klein, Douglas D. Reh, Lisa M. Rooper, Vafi Salmasi, Rafael J. Tamargo, Qing Wang, Tara Williamson, Tianna Zhao, Ying Zou, Alan K. Meeker, Nishant Agrawal, Bert Vogelstein, Kenneth W. Kinzler, Nickolas Papadopoulos, Chetan Bettegowda
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/666203899eb144b58109b82017f4bbe7
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spelling oai:doaj.org-article:666203899eb144b58109b82017f4bbe72021-12-02T15:34:14ZGenomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma10.1038/s41467-018-07578-z2041-1723https://doaj.org/article/666203899eb144b58109b82017f4bbe72018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07578-zhttps://doaj.org/toc/2041-1723Olfactory neuroblastoma (ONB) is a rare malignant tumor whose genetic basis is poorly understood. Here the authors identify recurrent deletions involving dystrophin in the majority of ONB patient tumors examined.Gary L. GalliaMing ZhangYi NingMichael C. HaffnerDenise BatistaZev A. BinderJustin A. BishopChristine L. HannRalph H. HrubanMasaru IshiiAlison P. KleinDouglas D. RehLisa M. RooperVafi SalmasiRafael J. TamargoQing WangTara WilliamsonTianna ZhaoYing ZouAlan K. MeekerNishant AgrawalBert VogelsteinKenneth W. KinzlerNickolas PapadopoulosChetan BettegowdaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-6 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gary L. Gallia
Ming Zhang
Yi Ning
Michael C. Haffner
Denise Batista
Zev A. Binder
Justin A. Bishop
Christine L. Hann
Ralph H. Hruban
Masaru Ishii
Alison P. Klein
Douglas D. Reh
Lisa M. Rooper
Vafi Salmasi
Rafael J. Tamargo
Qing Wang
Tara Williamson
Tianna Zhao
Ying Zou
Alan K. Meeker
Nishant Agrawal
Bert Vogelstein
Kenneth W. Kinzler
Nickolas Papadopoulos
Chetan Bettegowda
Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma
description Olfactory neuroblastoma (ONB) is a rare malignant tumor whose genetic basis is poorly understood. Here the authors identify recurrent deletions involving dystrophin in the majority of ONB patient tumors examined.
format article
author Gary L. Gallia
Ming Zhang
Yi Ning
Michael C. Haffner
Denise Batista
Zev A. Binder
Justin A. Bishop
Christine L. Hann
Ralph H. Hruban
Masaru Ishii
Alison P. Klein
Douglas D. Reh
Lisa M. Rooper
Vafi Salmasi
Rafael J. Tamargo
Qing Wang
Tara Williamson
Tianna Zhao
Ying Zou
Alan K. Meeker
Nishant Agrawal
Bert Vogelstein
Kenneth W. Kinzler
Nickolas Papadopoulos
Chetan Bettegowda
author_facet Gary L. Gallia
Ming Zhang
Yi Ning
Michael C. Haffner
Denise Batista
Zev A. Binder
Justin A. Bishop
Christine L. Hann
Ralph H. Hruban
Masaru Ishii
Alison P. Klein
Douglas D. Reh
Lisa M. Rooper
Vafi Salmasi
Rafael J. Tamargo
Qing Wang
Tara Williamson
Tianna Zhao
Ying Zou
Alan K. Meeker
Nishant Agrawal
Bert Vogelstein
Kenneth W. Kinzler
Nickolas Papadopoulos
Chetan Bettegowda
author_sort Gary L. Gallia
title Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma
title_short Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma
title_full Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma
title_fullStr Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma
title_full_unstemmed Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma
title_sort genomic analysis identifies frequent deletions of dystrophin in olfactory neuroblastoma
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/666203899eb144b58109b82017f4bbe7
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