THE IMPACT OF HEMATOLOGICAL PARAMETERS ON SURVIVAL FOR PATIENTS WITH COVID-19

Objective: Coronavirus disease 2019 is an infectious disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Clinical and laboratory predictors may identification of patients at risk of mortality and guide treatment .To analyze laboratory abnormalities in patients w...

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Autores principales:	Fatma YILMAZ, Murat ALBAYRAK, Hacer Berna AFACAN ÖZTÜRK, Senem MARAL, Ümit Yavuz MALKAN, Pınar AKYOL, Merih REİS ARAS, Buğra SAĞLAM, Mesut TIĞLIOĞLU, Abdülkerim YILDIZ
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Diseases of the blood and blood-forming organs RC633-647.5
Acceso en línea:	https://doaj.org/article/6666b030eae34e7dbaa3bbe3e3171e62
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spelling	oai:doaj.org-article:6666b030eae34e7dbaa3bbe3e3171e622021-11-10T04:32:55ZTHE IMPACT OF HEMATOLOGICAL PARAMETERS ON SURVIVAL FOR PATIENTS WITH COVID-192531-137910.1016/j.htct.2021.10.979https://doaj.org/article/6666b030eae34e7dbaa3bbe3e3171e622021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2531137921011263https://doaj.org/toc/2531-1379Objective: Coronavirus disease 2019 is an infectious disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Clinical and laboratory predictors may identification of patients at risk of mortality and guide treatment .To analyze laboratory abnormalities in patients with COVID-19 and define which parameters affect mortality and hospitalization Methodology: This retrospective study was conducted on 101 patients diagnosed with COVID-19. Demographic characteristics, laboratory parameters including complete blood count (CBC) parameters, biochemical tests, coagulation parameters, duration of hospitalization and final status (discharge or death) were recorded Results: Comparisons were made of survivors and non-survivors at the end of follow up period. Multivariate analysis showed mean platelet volume (MPV), platelet distribution width (PDW) and lactate dehydrogenase (LDH) to be significant predictors of mortality. The cut-off value of the hospitalization period was found to be 10 days, so patients were divided into two groups. In the multivariate models, no significant independent parameter was observed for the prediction of hospitalization duration. Conclusion: The results of the current study demonstrated that MPV, PDW and LDH were significant independent variables for the prediction of mortality. As SARS-CoV and SARS-CoV-2 are known to use the same receptor, there may be a similar structure and receptor for mutant variants and the first variant, so these predictive parameters can be considered to be as effective in mutant variants.Fatma YILMAZMurat ALBAYRAKHacer Berna AFACAN ÖZTÜRKSenem MARALÜmit Yavuz MALKANPınar AKYOLMerih REİS ARASBuğra SAĞLAMMesut TIĞLIOĞLUAbdülkerim YILDIZElsevierarticleDiseases of the blood and blood-forming organsRC633-647.5ENHematology, Transfusion and Cell Therapy, Vol 43, Iss , Pp S19-S20 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the blood and blood-forming organs RC633-647.5
spellingShingle	Diseases of the blood and blood-forming organs RC633-647.5 Fatma YILMAZ Murat ALBAYRAK Hacer Berna AFACAN ÖZTÜRK Senem MARAL Ümit Yavuz MALKAN Pınar AKYOL Merih REİS ARAS Buğra SAĞLAM Mesut TIĞLIOĞLU Abdülkerim YILDIZ THE IMPACT OF HEMATOLOGICAL PARAMETERS ON SURVIVAL FOR PATIENTS WITH COVID-19
description	Objective: Coronavirus disease 2019 is an infectious disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Clinical and laboratory predictors may identification of patients at risk of mortality and guide treatment .To analyze laboratory abnormalities in patients with COVID-19 and define which parameters affect mortality and hospitalization Methodology: This retrospective study was conducted on 101 patients diagnosed with COVID-19. Demographic characteristics, laboratory parameters including complete blood count (CBC) parameters, biochemical tests, coagulation parameters, duration of hospitalization and final status (discharge or death) were recorded Results: Comparisons were made of survivors and non-survivors at the end of follow up period. Multivariate analysis showed mean platelet volume (MPV), platelet distribution width (PDW) and lactate dehydrogenase (LDH) to be significant predictors of mortality. The cut-off value of the hospitalization period was found to be 10 days, so patients were divided into two groups. In the multivariate models, no significant independent parameter was observed for the prediction of hospitalization duration. Conclusion: The results of the current study demonstrated that MPV, PDW and LDH were significant independent variables for the prediction of mortality. As SARS-CoV and SARS-CoV-2 are known to use the same receptor, there may be a similar structure and receptor for mutant variants and the first variant, so these predictive parameters can be considered to be as effective in mutant variants.
format	article
author	Fatma YILMAZ Murat ALBAYRAK Hacer Berna AFACAN ÖZTÜRK Senem MARAL Ümit Yavuz MALKAN Pınar AKYOL Merih REİS ARAS Buğra SAĞLAM Mesut TIĞLIOĞLU Abdülkerim YILDIZ
author_facet	Fatma YILMAZ Murat ALBAYRAK Hacer Berna AFACAN ÖZTÜRK Senem MARAL Ümit Yavuz MALKAN Pınar AKYOL Merih REİS ARAS Buğra SAĞLAM Mesut TIĞLIOĞLU Abdülkerim YILDIZ
author_sort	Fatma YILMAZ
title	THE IMPACT OF HEMATOLOGICAL PARAMETERS ON SURVIVAL FOR PATIENTS WITH COVID-19
title_short	THE IMPACT OF HEMATOLOGICAL PARAMETERS ON SURVIVAL FOR PATIENTS WITH COVID-19
title_full	THE IMPACT OF HEMATOLOGICAL PARAMETERS ON SURVIVAL FOR PATIENTS WITH COVID-19
title_fullStr	THE IMPACT OF HEMATOLOGICAL PARAMETERS ON SURVIVAL FOR PATIENTS WITH COVID-19
title_full_unstemmed	THE IMPACT OF HEMATOLOGICAL PARAMETERS ON SURVIVAL FOR PATIENTS WITH COVID-19
title_sort	impact of hematological parameters on survival for patients with covid-19
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/6666b030eae34e7dbaa3bbe3e3171e62
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THE IMPACT OF HEMATOLOGICAL PARAMETERS ON SURVIVAL FOR PATIENTS WITH COVID-19

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