Antimicrobial properties of dental cements modified with zein-coated magnesium oxide nanoparticles

The aim of this study was to test the antimicrobial properties of dental cements modified with magnesium oxide (MgO) nanoparticles. Zein-modified MgO nanoparticles (zMgO) in concentrations (0.0, 0.3, 0.5, and 1.0%) were mixed with dental cements (Fuji II, Rely X Temp E, Ionoglass Cem, Es Temp NE, an...

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Autores principales:	Ghada H. Naguib, Hani M. Nassar, Mohamed T. Hamed
Formato:	article
Lenguaje:	EN
Publicado:	KeAi Communications Co., Ltd. 2022
Materias:	Magnesium oxide nanoparticles Antimicrobial biomaterials Dental cement Nanocoatings Materials of engineering and construction. Mechanics of materials TA401-492 Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/666807661536475c85571e6c1e9e6eaf
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id	oai:doaj.org-article:666807661536475c85571e6c1e9e6eaf
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spelling	oai:doaj.org-article:666807661536475c85571e6c1e9e6eaf2021-11-04T04:35:12ZAntimicrobial properties of dental cements modified with zein-coated magnesium oxide nanoparticles2452-199X10.1016/j.bioactmat.2021.06.011https://doaj.org/article/666807661536475c85571e6c1e9e6eaf2022-02-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2452199X21002978https://doaj.org/toc/2452-199XThe aim of this study was to test the antimicrobial properties of dental cements modified with magnesium oxide (MgO) nanoparticles. Zein-modified MgO nanoparticles (zMgO) in concentrations (0.0, 0.3, 0.5, and 1.0%) were mixed with dental cements (Fuji II, Rely X Temp E, Ionoglass Cem, Es Temp NE, and System P link). Eight discs were fabricated from each zMgO-cement pair for a total of 32 specimens for each cement. Characterization of the dental cements incorporating zMgO was done by X-ray Diffraction (XRD) and Field Emission Scanning Electron Microscopy (FESEM). The antimicrobial properties of the mixtures were tested using direct contact and agar diffusion assays against Streptococcus mutans, Staphylococcus aureus, Enterococcus faecalis, and Candida albicans. Data was analyzed using two-way analysis of variance and LSD post hoc test at 0.05 significance level. XRD spectra showed sharp peaks of zMgO indicating its high crystalline nature, while the amorphous dental cements with zMgO had broad peaks. FESEM analysis showed a uniform distribution of the zMgO nanoparticles in the cement. There were significant inhibition zone values associated with all concentrations of zMgO-cement mixtures tested compared to controls (p < 0.001) with a dose-response recorded only with Fuji II. Optical density values were significantly lower in zMgO groups compared to controls for all microorganisms. The effect was most prominent with Rely X against C. albicans and S. aureus. Dental cements containing zMgO showed significant antimicrobial properties that were dependent on the specific initial cement substrate.Ghada H. NaguibHani M. NassarMohamed T. HamedKeAi Communications Co., Ltd.articleMagnesium oxide nanoparticlesAntimicrobial biomaterialsDental cementNanocoatingsMaterials of engineering and construction. Mechanics of materialsTA401-492Biology (General)QH301-705.5ENBioactive Materials, Vol 8, Iss , Pp 49-56 (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Magnesium oxide nanoparticles Antimicrobial biomaterials Dental cement Nanocoatings Materials of engineering and construction. Mechanics of materials TA401-492 Biology (General) QH301-705.5
spellingShingle	Magnesium oxide nanoparticles Antimicrobial biomaterials Dental cement Nanocoatings Materials of engineering and construction. Mechanics of materials TA401-492 Biology (General) QH301-705.5 Ghada H. Naguib Hani M. Nassar Mohamed T. Hamed Antimicrobial properties of dental cements modified with zein-coated magnesium oxide nanoparticles
description	The aim of this study was to test the antimicrobial properties of dental cements modified with magnesium oxide (MgO) nanoparticles. Zein-modified MgO nanoparticles (zMgO) in concentrations (0.0, 0.3, 0.5, and 1.0%) were mixed with dental cements (Fuji II, Rely X Temp E, Ionoglass Cem, Es Temp NE, and System P link). Eight discs were fabricated from each zMgO-cement pair for a total of 32 specimens for each cement. Characterization of the dental cements incorporating zMgO was done by X-ray Diffraction (XRD) and Field Emission Scanning Electron Microscopy (FESEM). The antimicrobial properties of the mixtures were tested using direct contact and agar diffusion assays against Streptococcus mutans, Staphylococcus aureus, Enterococcus faecalis, and Candida albicans. Data was analyzed using two-way analysis of variance and LSD post hoc test at 0.05 significance level. XRD spectra showed sharp peaks of zMgO indicating its high crystalline nature, while the amorphous dental cements with zMgO had broad peaks. FESEM analysis showed a uniform distribution of the zMgO nanoparticles in the cement. There were significant inhibition zone values associated with all concentrations of zMgO-cement mixtures tested compared to controls (p < 0.001) with a dose-response recorded only with Fuji II. Optical density values were significantly lower in zMgO groups compared to controls for all microorganisms. The effect was most prominent with Rely X against C. albicans and S. aureus. Dental cements containing zMgO showed significant antimicrobial properties that were dependent on the specific initial cement substrate.
format	article
author	Ghada H. Naguib Hani M. Nassar Mohamed T. Hamed
author_facet	Ghada H. Naguib Hani M. Nassar Mohamed T. Hamed
author_sort	Ghada H. Naguib
title	Antimicrobial properties of dental cements modified with zein-coated magnesium oxide nanoparticles
title_short	Antimicrobial properties of dental cements modified with zein-coated magnesium oxide nanoparticles
title_full	Antimicrobial properties of dental cements modified with zein-coated magnesium oxide nanoparticles
title_fullStr	Antimicrobial properties of dental cements modified with zein-coated magnesium oxide nanoparticles
title_full_unstemmed	Antimicrobial properties of dental cements modified with zein-coated magnesium oxide nanoparticles
title_sort	antimicrobial properties of dental cements modified with zein-coated magnesium oxide nanoparticles
publisher	KeAi Communications Co., Ltd.
publishDate	2022
url	https://doaj.org/article/666807661536475c85571e6c1e9e6eaf
work_keys_str_mv	AT ghadahnaguib antimicrobialpropertiesofdentalcementsmodifiedwithzeincoatedmagnesiumoxidenanoparticles AT hanimnassar antimicrobialpropertiesofdentalcementsmodifiedwithzeincoatedmagnesiumoxidenanoparticles AT mohamedthamed antimicrobialpropertiesofdentalcementsmodifiedwithzeincoatedmagnesiumoxidenanoparticles
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Antimicrobial properties of dental cements modified with zein-coated magnesium oxide nanoparticles

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