Implicit water model within the Zimm-Bragg approach to analyze experimental data for heat and cold denaturation of proteins

In theoretical models, used to process experimental data on biopolymer conformations, the description of water-polymer interactions is challenging. Here the authors present a model that extracts the values of H-bonding energies and determines the conditions for cold denaturation from the energetic b...

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Autores principales: Artem Badasyan, Shushanik Tonoyan, Matjaz Valant, Joze Grdadolnik
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6668c53e3a064e2d9a3fc9b6f179b779
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Sumario:In theoretical models, used to process experimental data on biopolymer conformations, the description of water-polymer interactions is challenging. Here the authors present a model that extracts the values of H-bonding energies and determines the conditions for cold denaturation from the energetic balance.