Vesicular transport mediates the uptake of cytoplasmic proteins into mitochondria in Drosophila melanogaster

Mitochondrial dynamics change during ageing, with larger mitochondria and altered protein import in older animals. Here the authors show that Dosmit protein mediates mitochondrial morphology with Rab32 by inducing double-membraned vesicles that regulate protein trafficking into mitochondria.

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Bibliographic Details
Main Authors: Po-Lin Chen, Kai-Ting Huang, Chu-Ya Cheng, Jian-Chiuan Li, Hsiao-Yen Chan, Tzu-Yang Lin, Matthew P. Su, Wei-Yuan Yang, Henry C. Chang, Horng-Dar Wang, Chun-Hong Chen
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/666dd2760252480d98caf0dd4c44a027
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